Browsing Electronic Theses and Dissertations by Department "Chemistry"
Now showing items 301-320 of 363
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(2009-01-26)Department: ChemistryThe following dissertation is dedicated to the task of better understanding of the relationship between biology and nanomaterials. Specifically, how to apply biology in ways that will affect and influence nanomaterials, ...
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(2007-09-07)Department: ChemistryThe ultimate success of molecular imaging depends heavily upon discovery of selective imaging probes. This dissertation is focused on development, characterization and in vitro/in vivo imaging of novel imaging agents that ...
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(2010-08-09)Department: ChemistryThe content described in detail in this dissertation covers natural product guided drug discovery, traditional hit-to-lead medicinal chemistry and advances in total synthesis. The synthesis and biological evaluation of ...
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(2022-03-09)Department: ChemistryZwitterionic polysaccharides (ZPSs), an emerging class of carbohydrate antigens with novel T-cell activation capability, have gained interest from the scientific community due to the role of cell surface glycans in ...
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(2009-07-27)Department: ChemistryThe work presented in this thesis is the first example of alloy core/shell semiconductor nanocrystals. The synthesis of CdSxSe1-x/ZnS core/shells and their analysis by UV-Vis absorption spectroscopy, fluorescence spectroscopy, ...
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(2016-03-22)Department: ChemistryNew and innovative materials are needed to develop more effective batteries. Nanoscale materials such as graphite have unique properties only seen in the nano-regime that allow them to be used in the production of lithium-ion ...
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(2010-12-06)Department: ChemistryABSTRACT A A series of room temperature ionic liquids (RTILs) containing MX42- (where M = Co, Ni and X = Cl, I) as the counterion have been synthesized from alkyl imidazolium chlorides and the appropriate MX2 species. A ...
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(2007-10-08)Department: ChemistryMethylating agents react with DNA to give the cationic N7-methyl deoxyguanosine adduct, which can undergo hydrolytic opening of the imidazole ring to form 2,6-diamino-4-hydroxy-N5-(methyl)-formamido-pyrimidine (MeFAPy-dGuo) ...
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(2015-07-06)Department: ChemistryMeaningful advances in quantum dot-based technologies will require revolutionary advances in synthetic strategies and materials characterization. The development of an all solid-state quantum dot-sensitized solar cell and ...
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(2021-05-11)Department: ChemistryThe arimetamycins A-C are recently discovered anthracycline natural products that feature a conserved steffimycin aglycone adorned with various carbohydrates. Cytotoxicity evaluation against a panel of four cancel cell ...
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(2017-06-21)Department: ChemistryPreparation of various small inorganic and organometallic complexes was completed to determine their structural characteristics and potential applications. These compounds incorporated main group and early transition metals ...
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Synthesis and structures of main group organometallic complexes with sterically bulky allyl ligands (2009-07-25)Department: ChemistryThis work focuses on the synthesis and characterization of substituted allyl complexes of alkali metals and post-transition elements. The use of bulky trimethylsilyl substituents on the allyl ligands has afforded isolable ...
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(2019-03-27)Department: ChemistryThe cell is regulated by a vast network of dynamic protein interactions that facilitate various sub-cellular functions. To systematically monitor and characterize these transient and rapidly changing protein interactions, ...
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(2021-11-15)Department: ChemistryThe introduction of ferroelectric properties in quantum dots through cation exchange multiplies their already ever-growing list of applications, elevating their utility in industry. We report the appearance of ferroelectric ...
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(2018-05-16)Department: ChemistryCHEMISTRY Synthesis of Four Diastereomeric Linoleic Triols and Development of a Large Scale Convergent Approach to Apoptolidinone C Robert Woods Davis Dissertation under the direction of Professor Gary A. Sulikowski The ...
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(2017-12-08)Department: ChemistryRecent progress in nanotechnology has enabled rapid expansion at the interface of polymeric systems and biomedicine such that synthetic nanocarriers can be capable of entrapment and tunable releases of chemotherapeutics, ...
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(2023-01-09)Department: ChemistrySince the discovery that nonsteroidal anti-inflammatory drugs (NSAIDs) prevent pain, swelling, and inflammation by inhibiting the enzymes cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2), there has been interest in ...
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(2014-03-21)Department: ChemistryFeglymycin is a tridecapeptide that has been shown to act as an inhibitor of the formation of HIV syncytia as well as the cell-to-cell transmission of the virus. The natural product contains thirteen amino acid residues, ...
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(2016-04-07)Department: ChemistryThe rational design of hybrid nanoparticles is a powerful tool in harnessing nanoscale properties of several different materials in a single whole. The first portion of this work describes the synthesis of dual-plasmonic ...
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Synthetic Strategies Toward Complex Molecule Synthesis: from Glycan Mimetics to Complex Terpenoids (2024-03-08)Department: ChemistryGlycans are ubiquitously expressed on the surface of cells and are responsible for mediating a host of critical cellular interactions. Specifically, bacteria have evolved to produce a diverse array of carbohydrate structures ...