Electronic Theses and Dissertations
This collection holds electronic theses and dissertations of masters and doctoral students submitted to the Graduate School.
Authors retain copyright to their works.
Collections in this community
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Electronic Theses and Dissertations
Electronic theses and dissertations of masters and doctoral students submitted to the Graduate School.
Recent Submissions
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(2023-07-11)Department: Biomedical EngineeringBreast cancer metastasis is initiated when cells break through basement membrane and migrate through the surrounding tissue before spreading throughout the body to colonize secondary sites. The primary tumor microenvironment, ...
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(2023-07-18)Department: Civil EngineeringModern power grids are in a time of significant change. Legacy generators, such as coal and nuclear generators, are retiring. New technologies, such as wind generators, solar generators, and distributed energy resources, ...
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(2023-06-15)Department: Molecular Pathology & ImmunologyTumor-specific CD8 T cells (TST) found in patients with cancer are unable to halt cancer progression. TST are dysfunctional and cannot produce effector cytokines or kill target cells1. TST dysfunction, also known as ...
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(2023-06-22)Department: Molecular Pathology & ImmunologyWomen have higher rates of severe asthma compared to men. Severe asthma is characterized by increased Th2-mediated eosinophils and/or Th17-mediated neutrophils in the airway, leading to increased airway hyperresponsiveness ...
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(2023-06-01)Department: PsychologyElucidating disorder- and domain-specific deficits within psychiatric and medically ill populations is a primary focus in the field of neuropsychology. Comparing overlapping and distinct patterns of cognitive functioning ...
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(2023-06-14)Department: MathematicsWe extend Lawvere-Pitts prop-categories (aka. hyperdoctrines) to develop a general framework for providing "algebraic'' semantics for nonclassical first-order logics. This framework includes a natural notion of substitution, ...
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(2023-06-05)Department: PharmacologyBrown adipose tissue (BAT) has in recent times been rediscovered in adult humans, and together with work from preclinical models, shown to have the potential of providing a variety of positive metabolic benefits. These ...
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(2023-06-14)Department: Human GeneticsArrhythmias are abnormal heart rhythms that represent a major cause of morbidity and mortality across the world. While environmental factors such as lifestyle, diet, and other exposures may influence disease susceptibility, ...
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(2023-04-19)Department: NeuroscienceSynaptic transmission forms the basis of neural communication, yet much of its fundamental mechanisms remains to be elucidated. In particular, evoked neurotransmitter release (which occurs in response to an action potential) ...
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Retinal Ganglion Cell Excitability and Adaptations to Ionic Stress in Glaucomatous Optic Neuropathy (2023-04-13)Department: NeuroscienceNeurodegenerative diseases are complex disorders that affect various regions and cells in the central nervous system, sharing common hallmark features of progression. Intrinsic and extrinsic stressors lead to shared ...
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(2023-03-29)Department: Biomedical EngineeringOsteoarthritis (OA) is a debilitating and prevalent chronic joint disease. Matrix metalloproteinase 13 (MMP13) is a key driver of OA, as it degrades collagen type 2 (CII), a key structural ECM component of cartilage. CII ...
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(2023-04-18)Department: Molecular Physiology & BiophysicsHypertension is a major risk factor for heart failure with preserved ejection fraction, and emerging evidence implicates inflammation as integral to its pathogenesis. Clinical samples from patients admitted with heart ...
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(2023-07-20)Department: Cancer BiologyAlthough selenium deficiency correlates with colorectal cancer (CRC) risk, the roles of the selenium-rich antioxidant selenoprotein P (SELENOP) in CRC remain unclear. In this study, we defined SELENOP’s contributions to ...
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(2023-07-21)Department: Earth & Environmental SciencesLarge swaths of floating pumice (pumice rafts) tens to thousands of kilometers in area can be a striking and potentially hazardous product of submarine eruptions. Recent work has suggested that isolated porosity may be ...
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(2023-07-21)Department: Earth & Environmental SciencesLarge swaths of floating pumice (pumice rafts) tens to thousands of kilometers in area can be a striking and potentially hazardous product of submarine eruptions. Recent work has suggested that isolated porosity may be ...
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(2023-07-20)Department: Cancer BiologyAlthough selenium deficiency correlates with colorectal cancer (CRC) risk, the roles of the selenium-rich antioxidant selenoprotein P (SELENOP) in CRC remain unclear. In this study, we defined SELENOP’s contributions to ...
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(2023-07-21)Department: Earth & Environmental SciencesLarge swaths of floating pumice (pumice rafts) tens to thousands of kilometers in area can be a striking and potentially hazardous product of submarine eruptions. Recent work has suggested that isolated porosity may be ...
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(2023-07-21)Department: Earth & Environmental SciencesLarge swaths of floating pumice (pumice rafts) tens to thousands of kilometers in area can be a striking and potentially hazardous product of submarine eruptions. Recent work has suggested that isolated porosity may be ...
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(2023-07-21)Department: Earth & Environmental SciencesLarge swaths of floating pumice (pumice rafts) tens to thousands of kilometers in area can be a striking and potentially hazardous product of submarine eruptions. Recent work has suggested that isolated porosity may be ...
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(2023-07-21)Department: Earth & Environmental SciencesLarge swaths of floating pumice (pumice rafts) tens to thousands of kilometers in area can be a striking and potentially hazardous product of submarine eruptions. Recent work has suggested that isolated porosity may be ...