RSS 1.0Electronic Theses and Dissertations
Electronic theses and dissertations of masters and doctoral students submitted to the Graduate School.
Authors retain copyright to their works.
Recent Submissions
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(2021-01-19)Department: Mechanical EngineeringThe objective of this dissertation is to characterize augmented spark impinging (torch) igniters. Torch igniters inject propellants into a small prechamber where a spark igniter imparts the activation energy to initiate ...
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(2020-11-20)Department: Chemical & Physical BiologyFaithful duplication of DNA lies at the center of DNA replication, defects in which can lead to cancer and other diseases of genomic instability. Generating copies of the two stands of the DNA duplex begins with synthesis ...
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(2020-11-19)Department: Electrical EngineeringTo extend Moore’s law, transformative changes have been implemented to maintain device scaling. In this dissertation, I focus on the state-of-the-art technologies for future logic and RF applications. The semiconductor ...
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(2020-11-18)Department: Chemical & Physical BiologyFor over 30 years, an HIV-1 vaccine has remained elusive due to the high mutability and tremendous levels of genetic diversity exhibited by the virus. Current research efforts have focused on understanding B cell-encoded ...
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(2020-11-18)Department: Microbe-Host InteractionsSERINC5 is a 10-12 transmembrane domain cellular protein that is incorporated into budding HIV-1 particles and reduces HIV-1 infectivity by inhibiting virus-cell fusion. HIV-1 susceptibility to SERINC5 is determined by ...
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(2020-11-17)Department: PharmacologyVolume Regulated Anion Channels (VRACs) encoded by the LRRC8 gene family play critical roles in myriad cellular processes and might represent druggable targets. The dearth of pharmacological compounds available for studying ...
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(2020-11-17)Department: Electrical EngineeringThis work provides a high-speed flash-analog-to-digital converter with an increased resistance to ionizing radiation, specialized for use in sub-50 nm Silicon-On-Insulator technology nodes. When applying Radiation Hardened ...
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(2020-11-18)Department: PsychologyIt has been known for some time that attention is often guided by what other people look at and speak about, which can in turn invoke inferences about the beliefs, desires, and goals that drive their forms of reference, a ...
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(2020-11-18)Department: Cancer BiologyThe American Cancer Society estimates that over 250,000 new cases of invasive breast cancer are diagnosed annually in the United States. Subtyping breast cancer and the identification of targeted therapies have greatly ...
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(2020-11-16)Department: PharmacologyMalignant migrating partial seizures of infancy is a rare, devastating form of epilepsy most commonly associated with gain-of-function mutations in the potassium channel, Slack. Not only is this condition almost completely ...
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(2020-11-16)Department: Biomedical InformaticsMedication adherence is a complex set of time-varying behaviors—filling, ingesting, and refilling medication at the right time and in the right manner—necessary to effective pharmacotherapy. Proper methods of quantifying ...
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(2020-11-16)Department: Biomedical EngineeringThe spinal cord is a narrow, cylindrical structure responsible for rapidly transmitting electrical signals throughout the nervous system and is the primary sensorimotor pathway for the human body. Therefore, damage to the ...
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(2020-11-16)Department: Learning, Teaching & DiversityDespite growing calls for teaching that is justice-oriented, such as culturally sustaining pedagogy, social justice mathematics, and anti-racist teaching, mechanisms and theories for supporting STEM teachers’ learning of ...
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(2020-11-12)Department: Electrical EngineeringCyber-physical systems -- physical processes that are controlled by computational frameworks across networks -- have seen a large scale digitalization and democratization due to the improvements in edge computing, the ...
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(2020-11-20)Department: AnthropologyThis study focuses on social change, resource management, cooperation, and fairness among Tzotzil-Maya communities in the highlands of Chiapas, southern Mexico. Maya groups in Chiapas have undergone drastic changes over ...
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(2020-11-18)Department: Computer ScienceIn the big data era, person-specific data are being collected in an unprecedented manner. Given the potential wealth of insights in personal data, many organizations aim to share data while protecting privacy by sharing ...
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(2020-11-18)Department: PsychologyA fundamental question in decision-making is how instructions can be used to influence behavior. Nowhere is this question more important than in the legal system, in which the fate and lives of individuals are in the ...
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(2020-11-06)Department: BiostatisticsElectronic health records (EHRs) provide unprecedented amounts of data, facilitating entirely new kinds of observational research studies. One valuable and challenging area of research enabled by these databases is ...
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(2020-11-19)Department: Microbe-Host InteractionsHelicobacter pylori colonizes the stomach in about half of the world’s population. Gastric colonization with H. pylori strains containing the cag pathogenicity island (cag PAI) is a risk factor for gastric adenocarcinoma ...
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(2020-12-06)Department: Cell & Developmental BiologyThe oncoprotein transcription factor MYC is a major driver of malignancy and a highly-validated target for development of anti-cancer therapies. It has, however, proven challenging to inhibit MYC directly. Novel strategies ...