Browsing Electronic Theses and Dissertations by Title
Now showing items 1-20 of 7147
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(2017-11-07)Department: Electrical EngineeringThree commercially available GaN-based HEMT RF power devices were irradiated with 1.8 MeV protons in three operational modes. The operational modes were semi-on, fully-on and RF-on. The former two modes were low and ...
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(2011-10-17)Department: Electrical EngineeringThe 1/f noise magnitude of n-channel metal-oxide-semiconductor field effect transistors is found to decrease by up a factor of ~3 after 18 years of room-temperature aging. This decrease is largest in devices with ...
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(2018-11-26)Department: Chemical EngineeringChinese hamster ovary (CHO) cells are the most commonly utilized host cell line for biomanufacturing monoclonal antibody (mAb) drugs and other therapeutic proteins. This dissertation describes the application of 13C metabolic ...
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(2014-11-25)Department: Chemical EngineeringWe have applied 13C metabolic flux analysis (13C MFA) to develop a system-wide understanding of the central carbon metabolism of Chinese hamster ovary (CHO) cells, the most widely used host for industrial production of ...
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(2010-05-17)Department: PhysicsThe radiosensitizing pharmaceutical iododeoxyuridine (IUdR) has been around since the 1950’s, but has never reached full efficacy due to a lack of practical activation radiation source in the suitable energy range. We have ...
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(2005-11-30)Department: PhysicsWe solve the Hartree-Fock-Bogoliubov (HFB) equations for deformed, axially symmetric even-even nuclei in coordinate space on a 2D lattice utilizing the Basis-Spline expansion method. Our 2D lattice HFB code is a highly ...
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(2024-07-09)Department: Leadership & Policy StudiesHealth and education are fundamentally linked, with each significantly impacting and relying on the other. Scholars have recognized the potential to enhance health outcomes through educational interventions and the benefits ...
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(2012-07-26)Department: Interdisciplinary Studies: Interdisciplinary PharmacologyA novel three dimensional stereoselective descriptor for use in ligand-based computer-aided drug design (CADD) is presented in this thesis. CADD is an important tool for drug discovery and ligand-based CADD involves the ...
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3D Supervised Learning for CT Hematoma Segmentation via Transfer Learning from a 2D Trained Network (2020-05-19)Department: Electrical EngineeringSupervised learning approaches are the most widely used models in medical image processing and tend to offer the highest level of accuracy when paired data and labels are available. However, manual labeling process is ...
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(2024-07-16)Department: Computer ScienceAbdominal computed tomography (CT) offers high-resolution tissue maps that facilitate the quantification of body composition. The existing longitudinal CT dataset from the Baltimore Longitudinal Study of Aging (BLSA) enables ...
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(2018-07-16)Department: ReligionThis dissertation revitalizes and revisits the historical category of polemic by arguing for the existence of a distinct subgenre within polemic that was constructed as oral university-style disputation. It does by first ...
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(2020-11-10)Department: BiostatisticsAutism spectrum disorder (ASD) is a group of complex neurodevelopment disorders with a strong genetic basis. Large scale sequencing studies have provided strong evidence for dozens of ASD risk genes. However, it is estimated ...
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(2018-07-22)Department: BiostatisticsOur brain network, as a complex integrative system, consists of many different regions. Each region has its own task and function and simultaneously shares structural and functional information. With the developed imaging ...
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(2011-08-08)Department: Hearing and Speech SciencesThe purpose of this study was to experimentally investigate the behavioral correlates of emotional reactivity and emotion regulation and their relation to speech (dis)fluency in preschool-age children who do (CWS) and do ...
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(2013-04-18)Department: HistoryFrom the 1920s to the 1940s, 350 colleges and more than 2,000 public schools throughout the South were using in their courses curricular materials designed to stress African-American achievements and point out the many ...
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(2014-06-25)Department: Chemical and Physical BiologyThe methylation state of DNA is important for gene expression, gene imprinting, X-chromosome inactivation, and transposon silencing in mammals and plants. DNA methylation is established by methyltransferases to mark a ...
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(2013-12-05)Department: Human GeneticsMany recent studies have identified rare variants that contribute to common, complex disease. It is believed that rare variants likely have a larger effect size (compared to GWAS findings) and can act alone, in concert ...
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(2009-01-02)Department: Environmental EngineeringThis work consists of constructing a model that combines an understanding of physical transport processes and the biological mechanisms involved in the uptake, transport and sequestration of contaminants by a hyperaccumulator, ...
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(2013-06-17)Department: Human GeneticsA BIPHASIC ROLE FOR THE VOLTAGE-GATED SODIUM CHANNEL SCN5LAB IN CARDIAC DEVELOPMENT OF ZEBRAFISH JEFFREY S. BENNETT Dissertation under direction of Professor Dan M. Roden, M.D. Voltage-gated sodium channels (VGSCs) play ...
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(2019-07-30)Department: HistoryThe British coffeehouse has been the recipient of immense scholarly attention since Jürgen Habermas identified it as the paradigm of his public sphere, a space in which private and public interests intersected. But all of ...