Browsing Electronic Theses and Dissertations by Department "Chemistry"
Now showing items 201-220 of 363
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(2019-03-27)Department: ChemistryIon mobility (IM) is an important electrophoretic technique where gas-phase ions are separated by their collision cross section (CCS). Often, it is integrated with mass spectrometry, allowing separation of both ion size ...
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(2022-03-28)Department: ChemistryMass spectrometry-based untargeted metabolomics aims to comprehensively characterize the varied and critical roles of molecular species in biological systems. Due to the complexity of the samples as well as the prevalence ...
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(2021-03-23)Department: ChemistryMass spectrometry (MS) has been a rapidly growing analytical technique, especially when analyzing complex biological matrices in metabolomics, clinical applications, anti-doping applications, and routine testing analyses. ...
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(2021-03-23)Department: ChemistryAdaptive immunity, the specified, targeted response of the immune system to pathogens or mutated cells, is integral to survival of many organisms. The malfunction of the adaptive immunity response in humans results in many ...
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(2007-12-04)Department: ChemistryNanocarbon materials, specifically graphitic carbon nanofibers (GCNFs) and ultra-dispersed nanodiamond (UDD) particles, have attracted tremendous attention due to their specific nanometer scale structures and unique thermal, ...
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(2009-11-02)Department: ChemistryDifferent applications using gold at the nanoscale level are discussed in this dissertation. The first section includes relevant background into nanoparticles, specifically, monolayer protected gold clusters (MPC), and ...
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(2010-04-02)Department: Chemistryα,β-Diamino acids and β-amino acids are important constituents in countless natural products. These atypical amino acids often display interesting and useful biological properties and have also been used as useful building ...
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(2015-07-06)Department: ChemistryCHEMISTRY NEW METHODS TO INDUCE AND DETECT MICROBIAL SECONDARY METABOLITE PRODUCTION C. RUTH MCNEES Dissertation under the direction of Professor Brian O. Bachmann Secondary metabolite production by bacteria, particularly ...
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(2006-05-01)Department: ChemistryThe chemistry of acrolein and crotonaldehyde-derived propano-deoxyguanosine (γ-OH-PdG and α-CH<sub>3</sub>-γ-OH-PdG) adducts was monitored in the 5´-CpG-3´ sequence within a dodecamer duplex by NMR spectroscopy, in situ, ...
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(2011-04-06)Department: ChemistryReal-time electrochemical monitoring of cellular metabolism has revolutionized traditional toxicology by providing immediate insights into the effects of cellular stress on metabolism. The multi-analyte microphysiometer ...
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(2004-11-09)Department: ChemistryCHEMISTRY NOVEL METHODS IN CHROMATOGRAPHIC SEPARATIONS: NEW CHIRAL STATIONARY PHASES AND MOLECULAR TAGGING JORDAN DANIELLE HANEY BLODGETT Dissertation under the direction of Professor David M. Hercules A major obstacle ...
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(2016-10-12)Department: ChemistryThe work presented in this dissertation focuses on biomimetic studies of two systems of biosilification: a subset of unicellular algae, known as diatoms, and sea sponges. Chapter I introduces the topics represented in ...
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(2021-08-16)Department: ChemistryAs a means to prepare enantioenriched small molecules, chiral hydrogen bond catalysts have been developed. These organocatalysts are the latest broad class of reagents for enantioselective reaction development, but they ...
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(2021-03-25)Department: ChemistrySolvent-based synthesis has been the foundation of chemistry since the inception of synthetic transformations. As chemists become more aware of the chemical and environmental complications that arise from the use and ...
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(2009-04-27)Department: ChemistryK-26 is an acidic tripeptide molecule with ACE inhibitory activity. It represents one of three distinct classes of unique phosphonate containing compounds found in nature. Previous work has found that unlike other C-P ...
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(2014-04-16)Department: ChemistryThe search for active demethylation processes lead to discovery of 5-hydroxymethylcytosine (5hmC) adduct in the mammalian DNA. This lesion is formed post-replicatively by oxidation of ...
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(2012-12-12)Department: ChemistryThis research work aims to provide biochemical characterization of the enzyme(s) responsible for deoxyaminosugar oxidation in several glycosylated natural products. The enzyme homologues ORF36 and RubN8 from the everninomicn ...
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(2006-12-12)Department: ChemistryDevelopments at the interface between biology and nanoscale materials are crucial for the success of bionanotechnology in academic and industrial endeavors. An early development was made in assembling biological antibodies ...
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(2006-04-12)Department: ChemistryDissertation under the direction of Professor David Wilson Wright The fusion protein of the recently discovered human metapneumovirus (hMPV) was shown to be a homolog of previously characterized type I integral membrane ...
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(2014-10-06)Department: ChemistryK-26 and related (R)-AHEP containing natural products have been described as some of the most potent natural product inhibitors of human angiotensin-I converting enzyme (ACE) a physiologically important enzyme central to ...