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Field Emitters and Supercapacitors Based on Carbon Nanotube Films
(2009-12-09)
This research is focused on the synthesis of CNTs using thermal chemical vapor deposition (CVD) at atmospheric pressure with Pd, Ni, and Co as catalysts, and characterization of the CNTs for field emission applications. ...
The role of hemozoin in disease: oxidative stress
(2009-12-16)
Infecting 200 million people chronically, Schistosoma mansoni, the helminth responsible for schistosomiasis, catabolizes host hemoglobin releasing amino acids and heme. To avoid the oxidative stress caused by toxic free ...
Designer nanoparticles to detect and treat disease
(2009-12-02)
Conjugation of targeting, imaging and drug molecules to nanoparticles has been a developing area of interest over the last 10-15 years. Although great strides have been made, characterization and activity of functionalized ...
Understanding the impact of health information exchange technology: workflow elements, patterns of use, and information ecologies
(2009-11-30)
The concept of health information exchange (HIE) among organizations in the United States has evolved over the last 25 years, from early efforts to build Community Health Information Networks to recent collaborations in ...
Chiral proton catalysis: development of diastereo- and enantioselective syntheses of vicinal diamines and α,β-diamino acids
(2009-12-03)
1,2-Diamines form an important class of compounds, some members of which are valuable for their biological activity. In addition, chiral, non-racemic 1,2-diamines have emerged as an important class of ligands for ...
Relationship between Drs2 and Kes1 controlling protein trafficking in <i>Saccharomyces cerevisiae</i>
(2009-12-02)
Dissertation under the direction of Professor Todd R. Graham
Drs2 is a type IV P-type ATPase that catalyzes a phospholipid flippase activity in the trans-Golgi network (TGN) in Saccharomyces cerevisiae. Strains harboring ...
Investigation of hemi-gap-junction channels in retinal horizontal cells
(2009-12-02)
Hemi-gap-junction (HGJ) channels composed of connexin (Cx) proteins are proposed as the key component to mediate the negative feedback pathway from horizontal cells (HCs) to photoreceptors in the outer retina. The goal of ...
Analysis of Bves function in vesicular transport and cell morphology
(2009-12-14)
Bves is a transmembrane protein that influences cell migration, motility, and epithelial integrity through previously undefined mechanisms. In this dissertation, I present evidence that identifies the molecular basis for ...
The role of leptin in macrophage-driven aortic root lesion formation and of macrophage inflammatory protein-1α in leukocyte infiltration of white adipose tissue
(2009-12-11)
Obesity is a strong risk factor for type 2 diabetes and cardiovascular disease partly because of the changes that occur in white adipose tissue (WAT) during weight gain. As obesity progresses, WAT expands, becomes ...
Novel Methods for Variable Selection in Non-faithful Domains, Understanding Support Vector Machines, Learning Regions of Bayesian Networks, and Prediction Under Manipulation
(2009-12-11)
The focus of my research was to develop several novel computational techniques for discovering informative patterns and complex relationships in biomedical data. First, an efficient, heuristic method was developed to ...