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Interrogation of Biomolecular Interactions Utilizing Backscattering Interferometry
(2009-12-07)
Backscattering interferometry (BSI) is a relatively new technique used to study molecular interactions in a label-free format and is proving to be a versatile biosensing technique. BSI quantifies minute changes in refractive ...
The role of vascular endothelial growth factor-A (VEGF-A) in pancreatic islet function in adults
(2009-12-07)
MOLECULAR PHYSIOLOGY AND BIOPHYSICS
The Role of Vascular Endothelial Growth Factor-A (VEGF-A) in Pancreatic Islet Function
in Adults
JEANNELLE A. KANTZ
Thesis under the direction of Professor Dr. Alvin Powers
Pancreatic ...
Spatiotemporal stimulus effects on response properties of neurons in the primary somatosensory cortex of owl monkeys
(2009-12-10)
I investigated how tactile stimuli applied to different parts of one hand and to both hands affect neuronal response properties in primary somatosensory cortex (area 3b) of owl monkeys. The premise of this research is that ...
Mitigation of Radiation-induced Soft Errors Using Temporal Embedded Signature Monitoring
(2009-12-14)
Soft errors can alter the correct execution of code within a microprocessor, particularly if control logic is compromised. This thesis addresses the vulnerability of a microprocessor’s control logic by assigning a signature ...
Charge generation by secondary particles from nuclear reactions in back end of line materials
(2009-12-10)
Direct charge collection measurements are presented which prove that the presence of tungsten near sensitive volumes leads to extreme charge collection events through nuclear reactions. We demonstrate that, for a fixed ...
A biophysically based framework for examining phytoremediation strategies: optimization of uptake, transport and storage of cadmium in alpine pennycress (Thlaspi caerulescnes)
(2009-01-02)
This work consists of constructing a model that combines an understanding of physical transport processes and the biological mechanisms involved in the uptake, transport and sequestration of contaminants by a hyperaccumulator, ...
A Label-Free Method for the Determination of Polyethylene-Glycol Functionalization Efficiency on Gold Monolayer Protected Clusters
(2009-12-15)
Most bionanotechnology-based agents require careful control of surface properties to improve vascular circulation time, control delivery characteristics and provide biocompatibility, especially when used for diagnostics ...
Correlating MR relaxation measurements with corresponding proteomic information provided by MALDI IMS
(2009-12-08)
The premise of this work is to understand the contrast variations seen in MRI in light of the proteomic composition of tissue. Magnetic resonance imaging (MRI) is now widely used as a primary medical imaging method to ...
Design of a Multi-Disc Electromechanical Brake
(2009-11-19)
This thesis presents the design of an electrically-actuated, proportional brake that provides a significantly greater torque-to-weight ratio than a magnetic particle brake (considered a benchmark of the state-of-the-art) ...
The Myt1 and Ngn3 feed-forward expression loop drives pancreatic islet differentiation in the mouse
(2009-11-30)
In humans, the proper growth and homeostasis of endocrine islets in the pancreas is of great medical importance, in that loss and dysfunction of islet cells result in Type 1 and Type 2 Diabetes Mellitus. One of the major ...