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Trajectory Optimization and Machine Learning Radiofrequency Pulses for Enhanced Magnetic Resonance Imaging
(2017-11-27)
High field magnetic resonance imaging (MRI) offers several advantages over imaging at low field strengths, namely increased spectral resolution, better contrast due to longer T1 relaxation, higher signal to noise ratio ...
Cell Size-Selective MRI for Characterizing Brain Lesions in Rodent Models of Tumor and Radiation Necrosis
(2022-05-03)
Patients who have undergone radiation therapy for brain metastases often have latent lesions such as recurrent tumor or radiation necrosis. Differentiating these lesions in vivo is critical for providing adequate care, but ...
Explainable AI in Medical Imaging: Interpreting Multi-Modality Inference with Neuroimaging and EHR
(2022-11-07)
Medical image processing is the art and science of extracting clinically meaningful information from medical images. One exciting facet of this field is multi-modal modeling: combining various sources of medical data into ...
Advancements in Saturation Transfer Imaging of the Spinal Cord
(2020-11-16)
The spinal cord is a narrow, cylindrical structure responsible for rapidly transmitting electrical signals throughout the nervous system and is the primary sensorimotor pathway for the human body. Therefore, damage to the ...
Structural and functional evaluation of the human midbrain dopaminergic system using high resolution MRI at 7 T
(2012-03-31)
The midbrain dopamine system located within the ventral tegmental area (VTA) and substantia nigra (SN) contain dopaminergic (DA) neurons that are known to mediate various goal directed behaviors. Although research with ...
Gray Matter Surface-based Spatial Statistics in Neuroimaging Studies
(2019-03-22)
Neuroimaging provides an opportunity to gain valuable insight onto the microstructural changes in the brain associated with healthy growth and neurological disorders when conducting longitudinal or cross sectional studies. ...
Investigation of the Effect of Tissue Water Dynamics on Compartmental MRI Measurements using Contrast Enhanced Relaxometry and SPECT
(2012-04-11)
Magnetic resonance imaging (MRI) provides methods for characterizing tissue micro-structure using relaxation-based measurements with and without the use of contrast agents (CA). Two techniques, dynamic contrast enhanced ...
Improved Assessment of Reading Networks in the Brain Using Diffusion MRI
(2013-04-01)
Reading is a complex cognitive behavior, which relies on the incorporation of a network of brain regions. White matter is the information transfer pathway between distant brain regions, and thus plays an important role in ...
Transmit Radio-Frequency Field Mapping In High Field Magnetic Resonance Imaging
(2013-04-12)
A fast approach to reconstruct transmit RF field (|B1+|) maps in high field parallel Magnetic Resonance Imaging is presented in this thesis. First the concepts of parallel imaging reconstruction and the Bloch-Siegert (BS) ...
Myelin sensitivity in quantitative magnetization transfer and diffusion tensor imaging in an animal model of multiple sclerosis
(2015-04-17)
Conventional MRI is sensitive to detect brain abnormalities non-invasively through excellent contrast generated by variation in relaxation times and water proton density. However, conventional MRI lacks the specificity and ...