Browsing Electronic Theses and Dissertations by Department "Cell and Development Biology"
Now showing items 1-7 of 7
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(2009-12-14)Department: Cell and Development BiologyBves is a transmembrane protein that influences cell migration, motility, and epithelial integrity through previously undefined mechanisms. In this dissertation, I present evidence that identifies the molecular basis for ...
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(2005-07-18)Department: Cell and Development BiologyFertilization is a complex process involving several steps, including sperm activation, oocyte maturation, chemotaxis, gamete recognition, and cell fusion. Many of these essential steps are controlled and regulated by ...
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(2008-04-15)Department: Cell and Development BiologyExport of mature, translationally competent messenger ribonucleoprotein particles (mRNPs) from the nucleus to the cytoplasm is a highly orchestrated process that includes transcription, capping, splicing, and 3' end ...
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(2009-12-07)Department: Cell and Development BiologyThis project characterizes CENP-F protein function at a cellular and organ level. First, I outline our plan used to identify novel binding partners. The first binding partner I describe is syntaxin 4 and the interaction ...
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(2008-03-26)Department: Cell and Development BiologyEach time budding yeast divide they ensure that both the mother and daughter cell inherit a vacuole. Because budding yeast divide asymmetrically by budding, the vacuole must be actively transported into the bud. As the ...
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(2007-08-02)Department: Cell and Development BiologyKidney development in mammals is characterized by reciprocal tissue interaction between the ureteric bud and the metanephric mesenchyme. The outgrowing epithelial bud invades the overlying mesenchyme, inducing epithelial ...
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(2006-12-04)Department: Cell and Development BiologyThe transcription factor Pancreatic and duodenal homeobox 1 (Pdx1) is essential for formation of the pancreas and for glucose-responsive insulin secretion from mature pancreatic beta cells. In humans and mice, heterozygosity ...