Browsing Electronic Theses and Dissertations by Department "Cell & Developmental Biology"
Now showing items 1-20 of 55
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(2022-02-16)Department: Cell & Developmental BiologyWhen an organism is injured, the damaged tissue recognizes the presence and severity of the wound and rapidly responds to repair the injury and restore proper tissue functionality. But how do cells first detect the presence ...
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(2024-03-19)Department: Cell & Developmental BiologyA TALE OF TWO STROMAL COMPONENTS: INFLUENCE OF FIBROBLASTS, INNATE LYMPHOID CELLS TYPE 2, AND INTERLEUKIN 13 IN STOMACH METAPLASIA Gastric cancer is one of the leading causes of cancer mortality worldwide, however, key ...
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(2020-01-17)Department: Cell & Developmental BiologyBasement membranes are sheet-like extracellular matrixes that can be found on the basal surface of epithelial and endothelial cells, surrounding muscles and other organs, and in association with neurons. In addition to ...
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(2024-03-15)Department: Cell & Developmental BiologyAll organisms have developed strategies to respond to injury. Some tissues induce compensatory proliferation of surrounding cells which migrate into and invade the wound site. However, alternative strategies exist such as ...
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(2022-05-16)Department: Cell & Developmental BiologyThe ventral actin cytoskeleton is a dynamic network of actin stress fibers (VSFs) and focal adhesions that produces contractile forces integral in cell polarization, migration and extracellular matrix remodeling. My research ...
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(2020-07-22)Department: Cell & Developmental BiologyHere, we characterize spatial distribution of the Golgi complex in human cells. In contrast to the prevailing view that the Golgi compactly surrounds the centrosome throughout interphase, we observe characteristic differences ...
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(2021-06-15)Department: Cell & Developmental BiologyMulticellular organisms adapt to the environment by sensing it and reacting to it through neuronal networks that are in place to transform a stimulus into a behavioral effect. A functional nervous system requires pruning ...
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(2023-04-10)Department: Cell & Developmental BiologyMicrovilli are actin-based surface protrusions that have been repurposed throughout evolution to fulfill diverse cell functions including mechanosensation in inner ear hair cells and nutrient absorption in transporting ...
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(2021-04-02)Department: Cell & Developmental BiologyCancer is a heterogeneous disease displaying a variety of cell populations inter- and intra-tumorally. This heterogeneity poses a challenge to cancer treatment, as more heterogeneous cellular populations are more prone to ...
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(2024-03-08)Department: Cell & Developmental BiologyWDR5 is a highly-conserved nuclear protein which facilitates the assembly of histone-modifying complexes involved in a variety of chromatin-based, gene regulatory processes. WDR5 is best known for its role in scaffolding ...
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(2021-11-19)Department: Cell & Developmental BiologyDiabetic retinopathy (DR) is the leading cause of blindness in working age Americans. Chronic low-grade retinal inflammation is an essential contributor to the pathogenesis of DR, as it is known to drive many of the ...
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(2024-03-25)Department: Cell & Developmental BiologyMitochondrial and peroxisomal dynamics driven by DRP1 are integral to many cellular functions. Mutations in DRP1 lead to a devastating neurodevelopmental disease known as encephalopathy due to defective mitochondrial and ...
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(2024-03-25)Department: Cell & Developmental BiologyMitochondrial and peroxisomal dynamics driven by DRP1 are integral to many cellular functions. Mutations in DRP1 lead to a devastating neurodevelopmental disease known as encephalopathy due to defective mitochondrial and ...
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(2024-03-25)Department: Cell & Developmental BiologyMitochondrial and peroxisomal dynamics driven by DRP1 are integral to many cellular functions. Mutations in DRP1 lead to a devastating neurodevelopmental disease known as encephalopathy due to defective mitochondrial and ...
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(2024-03-25)Department: Cell & Developmental BiologyMitochondrial and peroxisomal dynamics driven by DRP1 are integral to many cellular functions. Mutations in DRP1 lead to a devastating neurodevelopmental disease known as encephalopathy due to defective mitochondrial and ...
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(2024-03-25)Department: Cell & Developmental BiologyMitochondrial and peroxisomal dynamics driven by DRP1 are integral to many cellular functions. Mutations in DRP1 lead to a devastating neurodevelopmental disease known as encephalopathy due to defective mitochondrial and ...
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(2024-03-25)Department: Cell & Developmental BiologyMitochondrial and peroxisomal dynamics driven by DRP1 are integral to many cellular functions. Mutations in DRP1 lead to a devastating neurodevelopmental disease known as encephalopathy due to defective mitochondrial and ...
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(2023-08-31)Department: Cell & Developmental BiologyThe ductus arteriosus (DA) is a muscular artery which helps to define the fetal pattern of the circulatory system. After birth, the DA undergoes muscular constriction and remodeling which establish the adult division between ...
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(2023-01-20)Department: Cell & Developmental BiologyMicrovilli are actin-bundle-supported surface protrusions that play essential roles in diverse epithelial functions, from nutrient absorption to mechanosensation. Despite the importance of microvilli for proper epithelial ...
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(2021-06-08)Department: Cell & Developmental BiologyDynamics and Regulation of Microtubule Minus Ends Microtubules are an integral part of the cytoskeletal system in cells and serve essential roles in cell division, intracellular transport, and morphogenesis. Microtubules ...