Browsing Electronic Theses and Dissertations by Author "Aaron Blaine Bowman"
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Bichell, Terry Jo Vetters (2016-12-06)Department: NeuroscienceHuntington’s disease (HD) is caused by an increase in CAG repeats in exon 1 of the huntingtin gene (HTT), which results in a polyglutamine expansion in the HTT protein. This mutation causes profound striatal neurodegeneration ...