Browsing Electronic Theses and Dissertations by Title
Now showing items 3285-3304 of 6747
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(2011-06-28)Department: Biological SciencesBIOLOGICAL SCIENCES KCTD12 PROTEINS REGULATE ULK2 TO CONTROL THE DEVELOPMENT OF ASYMMETRIC HABENULAR NEUROPIL ROBERT W. TAYLOR Dissertation under the direction of Professor Joshua T. Gamse The habenular nuclei (Hb) are ...
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(2006-11-28)Department: ReligionWhite conservative Protestants (fundamentalists, evangelicals, charismatics, and Pentecostals) in the early twenty-first century United States construct for themselves a religio-cultural identity by which they hold themselves ...
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(2017-12-06)Department: ReligionThis thesis will claim that applying the concepts of J.L Austin’s speech act theory to Søren Kierkegaard’s practice of indirect communication will provide insight into the performative aspects of indirect communication and ...
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(2009-07-25)Department: PhilosophyIn the abstract, this thesis focuses on the subject of philosophical doubt. Both Kierkegaard and Wittgenstein criticize philosophical doubt, and their methods of criticism are both similar and complimentary. In the first ...
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(2016-07-25)Department: Cell and Developmental BiologyThe Wnt signaling pathway plays essential roles in a wide variety of biological processes including early animal development, cell fate determination, cell proliferation, organogenesis, and stem-cell renewal. Deregulation ...
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(2010-08-03)Department: Cell and Developmental BiologyOne Immunological disorders of the gastrointestinal tract is inflammatory bowel disease (IBD). IBD results in recurrent and persistently elevated levels of cytokines, such as tumor necrosis factor (TNF). TNF promotes ...
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(2010-06-29)Department: Mechanical EngineeringStroke is one of the major causes of loss if dexterity in human hand, preventing effective self-care and employment opportunities among the patients. In this thesis, an exoskeleton device for thumb rehabilitation is ...
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(2006-03-30)Department: PharmacologyIn mammalian cells, phospholipase D activity is tightly regulated by diverse cellular signals including hormones, neurotransmitters, and growth factors. Multiple signaling pathways converge upon phospholipase D to modulate ...
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(2010-06-23)Department: BiochemistryThe kinetic characterization of cytochrome P450s that catalyze multi-step, sequential reactions is the focus of this work. Two novel substrates were identified for P450 1A2, one of which showed a high degree of homotropic ...
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(2010-04-16)Department: NeuroscienceGABA-A receptors are ligand-gated chloride channels that mediate the majority of fast inhibitory signaling in the central nervous system. Their kinetic properties determine the charge transfer and timing of inhibitory ...
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(2011-12-06)Department: ChemistryThe presented research describes how properties of thiolate protected gold nanoparticles were used to create functional nanomaterials with applications in biomimetics and nanomolecular electronics. Additionally, fundamental ...
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(2017-08-11)Department: Creative WritingThis manuscript of poetry contains three sections. The first section primarily includes poems about family landscapes, relationships, and history. These poems seek to explore past and present settings in order to understand ...
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(2009-04-02)Department: Leadership and Policy StudiesWhile there is ample criticism of principal certification and professional development programs to equip individuals with the expertise they need, we as a field possess few methodologies to measure leadership expertise. ...
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(2011-02-04)Department: Community Research and ActionThe flow of ideas that emerges from educational programs, particularly those that explicitly encourage interactions with community members, holds under-appreciated potential for knowledge flow to contribute to development ...
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(2008-06-06)Department: Biomedical InformaticsThis Master’s Thesis project had as its objectives: (1) to optimize algorithms for solvent-accessible surface area (SASA) approximation to develop an environment free energy knowledge-based potential; and, (2) to assess ...
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(2019-01-17)Department: PharmacologyG-protein coupled receptors (GPCRs) represent the largest family of membrane proteins and the most heavily targeted classes of proteins for therapeutic intervention. Relatively little is known about the structure of these ...
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(2010-12-21)Department: Human GeneticsGrowing interest and burgeoning technology for discovering genetic mechanisms that influence disease processes have ushered in a flood of genetic association studies over the last decade, yet little heritability in highly ...
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(2015-03-31)Department: SociologyThis qualitative study explores various toolsets Korean ethnic churches provide to Korean immigrant entrepreneurs. Based on twenty-four in-depth interviews with Korean business owners and co-owners, I question how immigration ...
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(2020-01-02)Department: Biological SciencesColorectal cancer (CRC) cells release protein-laden extracellular vesicles (EVs) that can alter the tumor microenvironment and spread drug resistance. I compared long RNAs of cells and matched EVs from isogenic CRC cell ...
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(2017-04-14)Department: Biological SciencesThere is growing evidence for the regulatory roles of extracellular RNAs (exRNAs) in mediating cell-to-cell communication. To test whether exosomal RNA might also contribute to changes in gene expression in recipient cells, ...