Browsing Electronic Theses and Dissertations by Department "Chemical Engineering"
Now showing items 61-80 of 151
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(2018-09-20)Department: Chemical EngineeringPerovskite nanocrystals have electronic and optical properties that could be advantageous in electronic devices. This dissertation aims to understand how post synthetic processing impacts the electron dynamics of CsPbBr3 ...
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(2020-08-26)Department: Chemical EngineeringAptamers are single-stranded oligonucleotide affinity reagents that are used for diagnostic and therapeutic applications. By adopting unique tertiary structures, aptamers can bind to a variety of targets, including inorganic ...
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(2020-05-19)Department: Chemical EngineeringHere, I develop and then further optimize 3pRNA-NPs: a nanoparticle delivery platform capable of activating the innate immune system through engagement of the cytosolic pattern recognition receptor RIG-I. Both targeting ...
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(2005-12-05)Department: Chemical EngineeringThis thesis is motivated by the need to improve performance of aerosol simulation in air quality models. I investigate the relationship between multicomponent aerosol sectional and modal distributions, which are the two ...
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(2014-05-30)Department: Chemical EngineeringCutaneous defects such as diabetic ulcers, severe burns, and traumatic injuries create a need for cost-effective wound care products that restore tissue function. This dissertation describes the development of an injectable ...
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(2015-04-02)Department: Chemical EngineeringOf the nearly 1.6 million bone graft procedures conducted annually to treat bone fractures in the U.S., ~25% of these fracture patients require rehospitalization due to graft failure. Injectable and settable synthetic bone ...
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(2022-05-16)Department: Chemical Engineering--
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(2024-01-03)Department: Chemical EngineeringThe overarching theme of the work presented herein is the combination of proteins with conducting polymers for the investigation of biohybrid and biomolecular-based electronics. While this topic is broad and encompasses ...
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(2005-07-23)Department: Chemical EngineeringGlycolysis and apoptotic cell death are integrated by the binding of hexokinase to the mitochondria where it has been reported that hexokinase phosphorylates glucose more efficiently and impedes apoptotic protein release ...
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Investigating Kinesin-based Mitotic Spindle Assembly Backup Mechanisms Using Single Molecule Methods (2018-04-02)Department: Chemical EngineeringMolecular motors are essential to sustain life, carrying out cellular processes that require directed motion over diffusion. Kinesins are motors that use ATP hydrolysis to perform mechanical work. Mitotic kinesins generate ...
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(2012-07-31)Department: Chemical EngineeringThe conversion of plant biomass to fermentable sugars is a primary option for the production of biofuels. Cellulases, the enzymes that break down recalcitrant plant cellulose materials into fermentable sugars, can be ...
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(2023-05-15)Department: Chemical EngineeringPorous silicon (PSi) has attracted interest as a nanomaterial with potential for optical biosensing, due to its high internal surface area, ease of fabrication, and versatile surface chemistry. Despite successful applications ...
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(2010-03-01)Department: Chemical EngineeringHeightened awareness in global warming and an increasing demand in energy consumption have generated a surging interest in creating sustainable alternative energy sources. One of the major challenges of incorporating ...
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(2012-12-05)Department: Chemical EngineeringDue to small surface area to volume ratios, nanoscale devices can exhibit dominant surface forces that can quickly degrade un-lubricated contacting surfaces. While fluorinated materials have been widely used as lubricants ...
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(2011-08-30)Department: Chemical EngineeringFuture innovations in a wide range of fields, from telecommunications to biomedical devices, will further push the boundaries of miniaturization and create a greater demand for microelectromechanical systems (MEMS). In ...
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(2015-11-30)Department: Chemical EngineeringPhotoautotrophic metabolism represents the primary source of all food on earth as well as raw materials for bio-based production of fuels and chemicals. Therefore, improving photosynthetic efficiency is an important aim ...
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(2011-04-14)Department: Chemical EngineeringRecent studies suggest that cancer cells undergo genotypic and phenotypic changes in response to the rigidity of the extracellular matrix (ECM). These studies have focused largely on non-mineralized tissues in the kPa range ...
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(2014-04-14)Department: Chemical EngineeringLipotoxicity from free fatty acid overload has been implicated in a variety of diseases including type II diabetes and non-alcoholic fatty liver disease (NAFLD). Incubation of hepatic cells in vitro with saturated fatty ...
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(2015-07-22)Department: Chemical EngineeringResearch attention is shifting towards renewable products made from microbial organisms altered using recombinant DNA technology. In metabolic engineering, these processes are optimized through iterative synthesis and ...
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Metabolic Mapping of Myc-Induced Lymphoma Models Using Isotopically Nonstationary 13C Flux Analysis (2013-04-16)Department: Chemical EngineeringIn recent years it has become evident that altered metabolism is a hallmark of cancer and offers many opportunities for therapeutic intervention. This dissertation presents the development of a novel metabolic flux analysis ...