Browsing Electronic Theses and Dissertations by Department "Pathology"
Now showing items 41-44 of 44
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(2014-06-24)Department: PathologyThe primary cause of morbidity and mortality in cystic fibrosis is progressive pulmonary disease, an important component of which is a hyperactive inflammatory response, the mechanisms of which are not completely understood. ...
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(2015-04-09)Department: PathologyBone formation during fracture repair inevitably initiates within, or around, extravascular deposits of a fibrin-rich matrix. In addition to a central role in hemostasis, fibrin is thought to enhance bone healing by promoting ...
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Therapeutic inhibition of the Wnt signaling pathway to promote regenerative repair of tissue injury (2016-04-07)Department: PathologyThe Wnt/Beta-catenin pathway is an evolutionarily conserved pathway whose role in regeneration of mammalian tissue injury is incompletely understood. The pathway is quiescent in most mammalian organs and is reactivated in ...
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(2012-03-31)Department: PathologyPatients with the autoimmune disease systemic lupus erythematosus (SLE) have an increased risk of developing premature cardiovascular disease, most notably atherosclerosis. While the mechanisms behind this increased risk ...