• About
    • Login
    View Item 
    •   Institutional Repository Home
    • Electronic Theses and Dissertations
    • Electronic Theses and Dissertations
    • View Item
    •   Institutional Repository Home
    • Electronic Theses and Dissertations
    • Electronic Theses and Dissertations
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of Institutional RepositoryCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsDepartmentThis CollectionBy Issue DateAuthorsTitlesSubjectsDepartment

    My Account

    LoginRegister

    Gold-coated magnetic polymer microsphere synthesis and characterization: applications in biological contexts

    Penamon, Phoebe
    : https://etd.library.vanderbilt.edu/etd-09172012-143249
    http://hdl.handle.net/1803/14166
    : 2012-09-28

    Abstract

    Gold-coated magnetic polymer microspheres (AuMPMs) are multi-component particles readily functionalized via gold-thiol chemistry, and can be strategically manipulated by a magnetic field. The research probes the uniformity, dispersity, stability, and conditions necessary for gold coating using a seed and growth method and functionalization of AuMPMs with thiolated ligands. The ligands, 6-amino-1-hexanethiol hydrochloride, 6-mercaptohexanoic acid, and 6-mercapto-1-hexanol, were utilized to impart a positive, negative, and neutral charge, respectively, to the surface of the AuMPM. Functionalized AuMPMs, were applied to a chamber and valve purification system to determine the effects of charged surfaces on the ability to overcome electrostatic interactions at the surface of the liquid-air and liquid-mineral oil interfaces of the chambers and valves. A platform technology is being developed that can easily coordinate and bind different ligands and can be utilized in a variety of biological, environmental, and analytical contexts.
    Show full item record

    Files in this item

    Icon
    Name:
    Penamon.pdf
    Size:
    1.103Mb
    Format:
    PDF
    View/Open

    This item appears in the following collection(s):

    • Electronic Theses and Dissertations

    Connect with Vanderbilt Libraries

    Your Vanderbilt

    • Alumni
    • Current Students
    • Faculty & Staff
    • International Students
    • Media
    • Parents & Family
    • Prospective Students
    • Researchers
    • Sports Fans
    • Visitors & Neighbors

    Support the Jean and Alexander Heard Libraries

    Support the Library...Give Now

    Gifts to the Libraries support the learning and research needs of the entire Vanderbilt community. Learn more about giving to the Libraries.

    Become a Friend of the Libraries

    Quick Links

    • Hours
    • About
    • Employment
    • Staff Directory
    • Accessibility Services
    • Contact
    • Vanderbilt Home
    • Privacy Policy