• About
    • Login
    View Item 
    •   Institutional Repository Home
    • Electronic Theses and Dissertations
    • Electronic Theses and Dissertations
    • View Item
    •   Institutional Repository Home
    • Electronic Theses and Dissertations
    • Electronic Theses and Dissertations
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of Institutional RepositoryCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Development of the SiliSPECT Small-Animal Imager

    McDonald, Benjamin Seth
    : https://etd.library.vanderbilt.edu/etd-04122010-010048
    http://hdl.handle.net/1803/12126
    : 2010-04-12

    Abstract

    SiliSPECT, a multi-pinhole, multi-detector SPECT system, was designed to image targeted regions of rodents at sub-300 micron resolution with stationary data acquisition. High spatial resolution is achieved with thick silicon double-sided strip detectors (DSSDs) and 250 micron pinhole apertures. Each of the two camera heads contain two stacked DSSDs, which collect four multi-pinhole projection images simultaneously, enhancing the total detection efficiency and permitting reconstruction based on the synthetic collimator method. The DSSDs were evaluated for imaging low-energy photons, such as the emissions from iodine-125. Trigger uniformity was improved with an iterative trim adjustment algorithm. Detection efficiency, dead time, charge-sharing, and other detector characteristics were measured. The system sensitivity, resolution, multiplexing and magnification of the full system were assessed. A calibration method was implemented to estimate the geometrical parameters of the system. SiliSPECT was fully characterized and readied for tomographic imaging studies.
    Show full item record

    Files in this item

    Icon
    Name:
    Dissertation.pdf
    Size:
    10.09Mb
    Format:
    PDF
    View/Open

    This item appears in the following collection(s):

    • Electronic Theses and Dissertations

    Connect with Vanderbilt Libraries

    Your Vanderbilt

    • Alumni
    • Current Students
    • Faculty & Staff
    • International Students
    • Media
    • Parents & Family
    • Prospective Students
    • Researchers
    • Sports Fans
    • Visitors & Neighbors

    Support the Jean and Alexander Heard Libraries

    Support the Library...Give Now

    Gifts to the Libraries support the learning and research needs of the entire Vanderbilt community. Learn more about giving to the Libraries.

    Become a Friend of the Libraries

    Quick Links

    • Hours
    • About
    • Employment
    • Staff Directory
    • Accessibility Services
    • Contact
    • Vanderbilt Home
    • Privacy Policy