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Roles of adhesion G protein-coupled receptors during zebrafish gastrulation and neuronal migration
(2013-07-31)
Gastrulation is a fundamental process during embryogenesis when the germ layers and shape of the animal are generated. Although the major cell movements during gastrulation have been characterized, the underlying cellular ...
A fully embedded Silicon On Insulator Total Ionizing Dose monitor
(2013-07-31)
Total ionizing dose (TID) effect is a kind of radiation effects. It’s related with the charge build up in the insulator caused by the radiation. This radiation induced charge build up will pose reliability issue and is a ...
Development and Control of a Multigrasp Myoelectric Hand Prosthesis
(2013-08-08)
Externally powered transradial prostheses have traditionally been limited to devices that are broad abstractions of the natural hand, possessing a single degree of freedom and having limited grasping capability. Enabled ...
A study of optoelectronic properties of carbon nanomaterials: transistors, sensors, and beyond
(2013-08-12)
The aims of this dissertation are to develop synthesis techniques for carbon nanomaterials, to investigate their electrical and optical properties, and to explore their applications in energy conversion and biological ...
Immanuel Kant and the Theory of Radical Democracy
(2013-08-16)
This dissertation is intended as an intervention in the interminable and apparently antinomical philosophical exchange between political theories of radical democracy descended from Ernesto Laclau and Chantal Mouffe and ...
Essays on the Interaction of Product Characteristics, Consumer Heterogeneity, and Information
(2013-10-07)
This dissertation addresses three related questions. The second chapter models a monopolist with private information about her product, over which consumers have heterogeneous preferences. Consumers may incur an audit ...
Targeting Gastrin-releasing Peptide in Neuroblastoma
(2013-09-04)
The overall survival for neuroblastoma remains dismal, in part due to the emergence of resistance to chemotherapeutic drugs resulting in aggressive, refractory disease. As a neuroendocrine tumor, neuroblastomas secrete a ...
DNA Damage Signaling Orchestrates SV40 Chromatin Replication
(2013-09-06)
The effects of DNA damage signaling on the DNA replication of the polyomavirus SV40 are examined in this dissertation. Infection of monkey cells with SV40 results in large amounts of cellular DNA damage signaling through ...
Biosynthetic Mechanisms of LTA-type Epoxides and Novel Bioactive Lipid Mediators
(2013-09-19)
Biosynthesis of lipid mediators including the leukotrienes, lipoxins, eoxins, resolvins, and protectins entails the lipoxygenase (LOX) catalyzed synthesis of an allylic epoxide intermediate, designated as leukotriene A4 ...
Uncertainty quantification in time-dependent reliability analysis
(2013-09-19)
The prediction of failure probability for engineering components/devices under service conditions often involves the use of predictive models and measurement data. The fact that no model is absolutely correct indicates the ...