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International Consortium for Health Outcomes Measurement (ICHOM): Standardized Patient-Centered Outcomes Measurement Set for Heart Failure Patients
(JACC-Heart Failure, 2020-03)
Whereas multiple national, international, and trial registries for heart failure have been created, international standards for clinical assessment and outcome measurement do not currently exist. The working group's objective ...
Impact of liver tumour burden, alkaline phosphatase elevation, and target lesion size on treatment outcomes with Lu-177-Dotatate: an analysis of the NETTER-1 study
(European Journal of Nuclear Medicine and Molecular Imaging, 2020-09)
Purpose To assess the impact of baseline liver tumour burden, alkaline phosphatase (ALP) elevation, and target lesion size on treatment outcomes with Lu-177-Dotatate. Methods In the phase 3 NETTER-1 trial, patients with ...
Sex hormone exposure and reproductive factors in pulmonary arterial hypertension: a case-control study
(Pulmonary Circulation, 2020-01)
Pulmonary arterial hypertension (PAH) is a sexually dimorphic disease that for unknown reasons affects women more than men. The role of estrogens, both endogenous and exogenous, and reproductive factors in this female ...
Reverse Cardio-Oncology: Cancer Development in Patients With Cardiovascular Disease
(Journal of the American Heart Association, 2020-01-21)
Diffusion time dependency along the human corpus callosum and exploration of age and sex differences as assessed by oscillating gradient spin-echo diffusion tensor imaging
(Neuroimage, 2020-04-15)
Conventional diffusion imaging uses pulsed gradient spin echo (PGSE) waveforms with diffusion times of tens of milliseconds (ms) to infer differences of white matter microstructure. The combined use of these long diffusion ...
BNST-insula structural connectivity in humans
(Neuroimage, 2020-04-15)
The bed nucleus of the stria terminalis (BNST) is emerging as a critical region in multiple psychiatric disorders including anxiety, PTSD, and alcohol and substance use disorders. In conjunction with growing knowledge of ...
Efficacy and safety of cap-assisted endoscopic mucosal resection of ileocecal valve polyps
(Endoscopy International Open, 2020-03)
Background and study aims Standard endoscopic mucosal resection (EMR) of ileocecal valve (ICV) polyps is challenging. Cap-assisted endoscopic mucosal resection (C-EMR) can be performed when polyps are not easily amenable ...
Updated nomenclature of delirium and acute encephalopathy: statement of ten Societies
(Intensive Care Medicine, 2020-02)
Ulcerative Colitis: Current and Emerging Treatment Strategies
(Journal of Clinical Medicine, 2020-01)
Historically, medical therapy for ulcerative colitis (UC) was limited to corticosteroids. Excitingly, over the past just 1-2 decades, the options for medical therapy have expanded and include biologics and small molecules, ...
Effects of Interleukin-1 beta Inhibition on Blood Pressure, Incident Hypertension, and Residual Inflammatory Risk A Secondary Analysis of CANTOS
(Hypertension, 2020-02)
While hypertension and inflammation are physiologically inter-related, the effect of therapies that specifically target inflammation on blood pressure is uncertain. The recent CANTOS (Canakinumab Anti-inflammatory Thrombosis ...