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Now showing items 11-20 of 33
Aerobic exercise training improves hepatic and muscle insulin sensitivity, but reduces splanchnic glucose uptake in obese humans with type 2 diabetes
(Nutrition & Diabetes, 2019-09-02)
Background: Aerobic exercise training is known to have beneficial effects on whole-body glucose metabolism in people with type 2 diabetes (T2D). The responses of the liver to such training are less well understood. The ...
Operative vs Nonoperative Treatment for Atraumatic Rotator Cuff Tears A Trial Protocol for the Arthroscopic Rotator Cuff Pragmatic Randomized Clinical Trial
(JAMA Networks Open, 2019-08)
IMPORTANCE Rotator cuff disorders remain the most common cause of shoulder pain and are among the most common reasons for patients to seek care in primary and specialty settings. Although operative and nonoperative treatments ...
Evaluation of Frailty as an Unmeasured Confounder in Observational Studies of Antidiabetic Medications
(Journals of Gerontology Series A-Biiological Sciences and Medicall Sciences, 2019-08)
Background: It is unknown whether observational studies evaluating the association between antidiabetic medications and mortality adequately account for frailty. Our objectives were to evaluate if frailty was a potential ...
GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network
(BMC Medicine, 2019-07-17)
BackgroundNon-alcoholic fatty liver disease (NAFLD) is a common chronic liver illness with a genetically heterogeneous background that can be accompanied by considerable morbidity and attendant health care costs. The ...
Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation
(Critical Care, 2019-07-23)
BackgroundIntravenous fluids, an essential component of sepsis resuscitation, may paradoxically worsen outcomes by exacerbating endothelial injury. Preclinical models suggest that fluid resuscitation degrades the endothelial ...
Interventions to prevent iatrogenic anemia: a Laboratory Medicine Best Practices systematic review
(Critical Care, 2019-08-09)
Background As many as 90% of patients develop anemia by their third day in an intensive care unit (ICU). We evaluated the efficacy of interventions to reduce phlebotomy-related blood loss on the volume of blood lost, ...
Optimism may moderate screening mammogram frequency in Medicare A longitudinal study
(Medicine, 2019-06)
Higher trait optimism and/or lower cynical hostility are associated with healthier behaviors and lower risk of morbidity and mortality, yet their association with health care utilization has been understudied. Whether these ...
Enteral Autonomy and Days Off Parenteral Support With Teduglutide Treatment for Short Bowel Syndrome in the STEPS Trials
(Journal of Parenteral and Enteral Nutrition, 2020-05)
Background Teduglutide response, in terms of parenteral support (PS) volume reduction, is associated with specific disease characteristics among adults with short bowel syndrome-associated intestinal failure (SBS-IF). ...
Associations between maternal social capital and infant birth weight in three developing countries: a cross-sectional multilevel analysis of Young Lives data
(BMJ Open, 2019-10)
Objective To explore how three indicators of social capital (ie, group membership, social support and cognitive social capital and specific types within each type) are associated with infant birth weight.
Study design ...
Functional outcomes associated with varying levels of targeted temperature management after out-of-hospital cardiac arrest - An INTCAR2 registry analysis
(2020-01-01)
Introduction: Targeted temperature management (TTM) after out-of-hospital cardiac arrest (OHCA) has been recommended in international guidelines since 2005. The TTM-trial published in 2013 showed no difference in survival ...