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Targeting K-Ras, Pak-1, And Mcl-1 for the Treatment of Cancer
(2015-11-24)
Malignant cancers are the second leading cause of death in the United States, with a projected 1.6 million new diagnoses per year and almost 600,000 deaths. Our understanding of the molecular pathways causing tumor initiation, ...
The Function of MTBP in Proliferation, Tumorigenesis and Tumor Cell Maintenance
(2014-07-22)
Although the MYC transcription factor was discovered over three decades ago and is dysregulated in the majority of human cancers, its regulation remains incompletely understood and there is no pharmacologic means to inhibit ...