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Development of Polyurethanes for Analysis and Treatment of Cancer Induced Bone Disease
(2014-04-15)
Overall cancer fatalities have stabilized since the early 1990s, however the prevalence of cancer is still remarkably high for men (45%) and women (38%). While the recent advances in treatments for cancers have increased ...
Development, Optimization and Evaluation of Tumor-Specific Nanosponge Drug Delivery Systems as Chemotherapeutics
(2014-12-03)
Current chemotherapeutic treatments for cancer utilize systemic administration of cytotoxic drugs and produce many side effects in healthy tissues, making optimal treatment of cancer hard to achieve. Tumor targeted ...
Folate-targeted proteolytic nanobeacons: towards selective, imaged delivery in solid tumors
(2014-11-26)
Cancer, a diagnosis that encompasses over 200 different disease states classified as malignant neoplasms, is poised to become the leading cause of death in the United States. Many of these diseases arise in the form of ...
Development of Albumin-Hitchhiking siRNA Conjugates for Therapeutic Mcl-1 Silencing in Triple Negative Breast Cancer
(2022-05-16)
Triple negative breast cancer (TNBC) is characterized by a lack of estrogen receptor, progesterone receptor, and HER2. Patients with TNBC therefore cannot benefit from treatment with one of the molecularly targeted therapies ...