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A Comprehensive Framework for Systems Immune Monitoring in Patients with Cancer
(2018-03-29)
The immune system is a complex network of cells spread throughout the body, spanning dozens of tissue types and locations. A complete understanding of a systemic immune response, like those required for the regression of ...
Self/tumor-reactive CD8 T cells enter a memory-like TCF1+ PD1- dysfunctional state
(2023-07-18)
T cells recognize several types of antigens in tumors, including aberrantly expressed, non-mutated proteins (self/shared-antigens; SSA) and mutated proteins or oncogenic viral proteins (tumor-specific antigens; TSA). ...
Self/tumor-reactive CD8 T cells enter a memory-like TCF1+ PD1- dysfunctional state
(2023-07-18)
T cells recognize several types of antigens in tumors, including aberrantly expressed, non-mutated proteins (self/shared-antigens; SSA) and mutated proteins or oncogenic viral proteins (tumor-specific antigens; TSA). ...