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Structural Studies of N6-(Deoxy-D-Erythro-Pentofuranosyl)-2,6-Diamino-3,4-Dihydro-4-Oxo-5-N-Methylformamido-Pyrimidine and 8-(Deoxyguanosin-N2-yl)-1-Aminopyrene
(2016-03-25)
N6-(Deoxy-D-Erythro-Pentofuranosyl)-2,6-Diamino-3,4-Dihydro-4-Oxo-5-N-Methylformamido-Pyrimidine (MeFapy-dG) is a deoxyribonucleic acid lesion that has been hypothesized to be induced by methylating chemotherapeutic agents. ...
Comparative Biochemical and Structural Analysis of the Alzheimer’s Disease Related Proteins: Amyloid Precursor Protein and Notch1.
(2016-03-29)
BIOCHEMISTRY
Comparative Biochemical and Structural Analysis of the Alzheimer’s Disease Related Proteins: Amyloid Precursor Protein and Notch 1.
Catherine Laura Deatherage
Dissertation under the direction of Professor ...
Spectroscopic Study of the Conformational Changes Involved in the Activation of CaMKII
(2016-07-22)
The CaMKII enzyme is involved in diverse biological processes including control of heart rate and synaptic plasticity. CaMKII is activated by binding of calmodulin (CaM) and ATP. Its intricate structure and dynamics are ...
Computational Design of Protein-Ligand Interfaces Using RosettaLigand
(2016-04-07)
Computational design of protein-ligand interfaces expands understanding of the basic forces involved in molecular recognition, and also contributes to the development of protein therapeutics. My dissertation research ...
gr-MRI: A Software Package for Magnetic Resonance Imaging Using Software Defined Radios
(2016-04-08)
Purpose: To develop software that enables the rapid implementation of custom MRI spectrometers using commercially-available software defined radios (SDRs).
Methods: The gr-MRI software package comprises a set of Python ...