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Improving Protein-Small Molecule Structure Predictions with Ensemble Methods, or Using Computers to Guess How Tiny Things Fit Together
(2018-08-06)
Protein-small molecule structure prediction, or protein-ligand docking, is a computational method for modeling how binding partners will interaction on an atomic level. Accurate prediction of protein-small molecule ...
Exceptionally Black New Orleans: Public Policy, Memory, and Ritual in “The City that Care Forgot”
(2018-08-15)
Post Katrina, given the disparate outcomes and dispersal rates for African Americans, residents of the city have questioned to what extent New Orleans is being intentionally reconfigured as a smaller, wealthier, and whiter ...
A Place Called Home: Dispossession and Remembrance of a Central NY Landscape
(2018-08-17)
Utilizing aspects of social, cultural, political, military and environmental history, this dissertation details the cycles of possession and dispossession of the lands of the Seneca Army Depot in upstate New York. It ...
Preschoolers' curiosity about novel words
(2018-08-29)
Children who become curious about words’ meanings may be making active, self-directed attempts at learning those words, but little is known about whether they have a preference to learn about novel words. In the current ...
Radiation effects on microelectromechanical systems
(2018-08-23)
The effects of ionizing radiation and displacement damage are two significant reliability
concerns for transducer applications in radiation environments. Microelectromechanical systems
(MEMS) are considered as potential ...
Statistical Methods for the Analysis of Error-Prone Electronic Health Records: Impact of Source Data Verification, Time Discretized Multiple Imputation, and Variance Estimation with Incompatible Imputation and Analysis Models
(2018-08-29)
Observational data from electronic health records (EHRs) are prone to errors which are often correlated across multiple variables. One strategy to assess EHR data quality is to compare the research study data to the original ...
The Role of Parent Stress and Parenting Behaviors in Cognitive Function in Children with Sickle Cell Disease
(2018-08-24)
Sickle cell disease (SCD) is a chronic, life-threatening condition that affects more than one every 400 African American newborns. In addition to being at greater risk for cognitive impairment, children with SCD are also ...
Inhibition of Diacylglycerol Lipase Impairs Fear Extinction in Mice
(2018-08-30)
Inhibition of Diacylglycerol Lipase Impairs Fear Extinction in Mice
Victoria S. Cavener
Dissertation under direction of Professor Sachin Patel
Elucidating the underlying molecular mechanisms regulating fear and extinction ...
A General Measure of Effect Size for Mediation Analysis
(2018-08-27)
Mediation analysis is an increasingly popular statistical method in the social sciences. However, currently available effect size measures for mediation have substantial limitations. In particular, complex mediation models ...
Mathematical Modeling of Heterogeneity and Drug Response in Lung Cancer
(2018-09-24)
Technological advances have led to increasingly powerful and precise quantification of biological systems. These advances create a need for robust mathematical and computational approaches that are able to integrate complex ...