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A Comparison of Approaches for Unplanned Sample Size Changes in Phase II Clinical Trials
(2017-06-20)
Oncology phase II clinical trials are used to evaluate the initial effect of a new regimen to determine if there warrants further study in a phase III clinical trial. Two-stage designs with an early futility stop are ...
Mechano-Electrochemistry for Advanced Energy Storage and Harvesting Devices
(2018-06-18)
A fundamental perception in the energy storage community is that mechanical processes accompanying electrochemical processes are an unavoidable by-product. However, the coupling between mechanics and electrochemistry termed ...
Saved “Out,” Sanctified “Out,” and Souled “Out”: A Critical Analysis of Disgust and the Prophetic Immanence of James Baldwin’s Gender Sexual Politics
(2019-06-14)
The “prophetic immanence” of James Baldwin’s racial and gender sexual politics as it relates to his experience with the black Christian church and the civil rights freedom struggle serves as symbol of hope, redemption and ...
Sequential Rematched Randomization and Adaptive Monitoring with the Second-Generation p-Value to increase the efficiency and efficacy of Randomized Clinical Trials
(2019-06-17)
Randomized Trials are considered the gold standard in establishing the benefit of an intervention with the overall societal benefit of knowledge gained outweighing the collective costs in time, money, human resources, etc. ...
Blackness and the Problem of Belonging: A Political Theology of Race and Reproduction
(2019-06-18)
This study contributes to a diagnosis of how Christian ideas of peoplehood fund imaginations of race in the United States. Where many scholars examine how the Christian designation of “chosen peoplehood” legitimates claims ...
Bridging High School and College: Supporting Enrollment for College-Intending High School Seniors in Tennessee
(2019-06-17)
This dissertation is comprised of three studies that examine the likelihood of exiting the college-going pipeline, test the framing of a text messaging intervention, and explore the transition and enrollment experience for ...
Predicting Colorectal Cancer Recurrence by Utilizing Multiple-View Multiple-Learner Supervised Learning
(2016-06-15)
Colorectal Cancer (CRC) remains a leading cause of cancer-related mortality in the United States. A key therapeutic dilemma in the treatment of CRC is whether patients with stage II and stage III disease require adjuvant ...
Essays on Trade Agreements and Export Dynamics
(2013-06-17)
The economic effects of the World Trade Organization (WTO) trade agreements
and firm level export dynamics are presented in this thesis. The first
chapter focuses on the dynamic aspects of most favored nation (MFN) tariffs
and ...
Probing Cell Mechanotransduction and Electric Activity with Microfluidic Platforms
(2017-06-16)
How cells detect and respond to mechanical, chemical, and electrical stimuli and make vital cellular decisions accordingly has been extremely puzzling and intriguing. Despite unremitting efforts of generations of researchers, ...
Three Essays in Health Economics: Evidence from U.S. Vaccination Policy
(2018-07-09)
In this dissertation I empirically examine a range of policies that have been implemented in the United States with the goal of achieving and maintaining high population vaccination rates. In the first chapter I focus on ...