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Mechanistically Distinct Modes of Endocannabinoid Mobilization at Glutamatergic Synapses of the Lateral Division of the Central Amygdala and Its Regulation by Chronic Stress
(2014-12-08)
The lateral division of the central amygdala (CeAL) is a key structure at the limbic-motor interface regulating stress-responses and emotional learning. Endocannabinoid (eCB) signaling is heavily implicated in the regulation ...
Biobehavioral Response to Social Judgment in Adolescents with Autism Spectrum Disorder
(2015-12-08)
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social behavior. It is unclear if deficits are due to disinterest in social stimuli, or to an elevated stress response. The ...
Mothers Coping with Childhood Cancer in the Context of Sociodemographic Disadvantage: Interactive and Longitudinal Effects on Depressive Symptoms
(2017-02-20)
The present study integrated and expanded upon two previously separate lines of research on stress and coping processes endemic to mothers faced with two significant sources of stress: mothers coping with a child’s cancer ...
The Effects of α2A-Adrenergic Receptors on Glutamatergic Signaling in the Bed Nucleus of the Stria Terminalis
(2014-09-10)
Drug addiction is a chronically relapsing disorder characterized by cycles of drug use, withdrawal, and relapse. Stress-induced relapse of drug use is a significant barrier to curing addiction. The bed nucleus of the stria ...
Dissecting the Stress Recruitment of BNST CRF Neurons: Regulation of Glutamatergic Inputs via Gi-coupled GPCR Signaling
(2018-09-18)
Stress contributes to numerous psychiatric disorders. CRF signaling in the bed nucleus of the stria terminalis (BNST) drives negative affective behaviors, thus agents that decrease activity of these cells may be of therapeutic ...
Stress, Negative Cognitive Style, and Coping as Predictors of Depressive Symptoms in Children of Depressed Parents
(2010-04-08)
Stress, negative cognitive style, and coping were studied as predictors of depressive symptoms in children and adolescents at risk for depression. This study examined 166 children and adolescents (ages 9 to 15) of depressed ...
A Comparison of Emotion Granularity in Managing Acute and Repeated Stress
(2015-04-02)
Emotion differentiation is emerging as a focus in emotion research due to its potential for enhancing regulation strategies, social functioning, and other valuable life outcomes. These studies aim to explore whether the ...
More than Discrimination: The Significance of Race-Based Stress and Racial Identity for the Mental Health of Black Americans
(2015-04-02)
Despite a large literature outlining the significance of racial discrimination for risk of poor health and well-being among black Americans, there is a growing recognition that current measures fail to reliably and ...
Laughter and Amusement’s Buffering Effect on Stress in a Population with Symptoms of Anxiety: An Experimental Design
(2016-04-08)
Anxiety and stress can have debilitating effects on our physical and mental health. The purpose of the current study was to examine a way to buffer, or protect, people with anxious symptoms from the negative affect produced ...
The Endocannabinoid, 2-arachidonoylglycerol, Regulates Resilience to Stress-induced Anxiety
(2017-04-10)
Nearly 30% of the global burden of nonfatal disease is due to affective disorders. Stress is a potent risk factor for affective disorders including major depression and posttraumatic stress disorder. The neurobiological ...