Browsing Electronic Theses and Dissertations by Title
Now showing items 4946-4965 of 6742
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(2019-04-17)Department: Molecular Physiology and BiophysicsErica JP Anderson Dissertation under the direction of Roger D Cone, PhD Energy stores in fat tissue are determined in part by the activity of the hypothalamic neurons expressing the melanocortin-4 receptor (MC4R). Even ...
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(2013-07-02)Department: Biological SciencesmicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at the post-transcriptional level by specific binding to recognition elements in the 3’ untranslated regions (UTRs) of target mRNAs. In zebrafish ...
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(2011-12-12)Department: PathologyIn this dissertation, I examined the function of the alpha2beta1 integrin in epithelial tumor cells as well as in the tumor microenvironment. The alpha2beta1 integrin is a surface heterodimeric receptor found on epithelial, ...
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(2018-03-28)Department: Microbiology and ImmunologyCoronaviruses (CoVs) are positive-sense RNA viruses that infect numerous mammalian and avian species and are capable of causing severe and lethal disease in humans. CoVs encode many innate immune antagonists that counteract ...
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(2014-07-25)Department: Molecular Physiology and BiophysicsLoss-of-function mutations causing haploinsufficiency of the MC4R are the most common monogenic cause of severe early-onset obesity in humans. Research has primarily focused on how central MC4R contributes to energy ...
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(2016-06-03)Department: NeuroscienceDespite the presence of a cytosolic fatty acid synthesis pathway, mitochondria have retained their own means of creating fatty acids via the mitochondrial fatty acid synthesis (mtFASII) pathway. The reason for its conservation ...
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(2010-12-09)Department: NeuroscienceThe presynaptic choline transporter (CHT, SLC5A7) supplies choline for acetylcholine (ACh) synthesis in cholinergic neurons. CHT is particularly important as the demands of cholinergic signaling increase and ACh stores ...
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(2006-04-04)Department: Biological SciencesThe temperature-sensitive (TS) paralyzed and blind Drosophila mutant rolling blackout (rbo) identifies a gene encoding a protein that pioneers a novel family of membrane-associated putative lipolytic enzymes highly conserved ...
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(2006-01-10)Department: ReligionRELIGION ROMANS 13 AND THE MARKET ECONOMY SUBJECTION, REFLECTION RESISTANCE: A THREE DIMENSIONAL PROCESS OF EMPOWERMENT MONYA A. STUBBS Dissertation under the direction of Professor Daniel Patte Critical biblical ...
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(2014-12-03)Department: HistoryThis paper examines the travel diaries and sketches of four Germans who traveled to the United States in the nineteenth century: Paul Wilhelm, Duke of Württemberg (1822-1824); Frederick Julius Gustorf (1835-1836); Albert ...
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(2017-04-12)Department: Mechanical EngineeringAs energy demand steadily increases, sulfur battery chemistries gain more and more attention for their promise to enable long-duration portable energy (Li-S system) and extremely low cost stationary storage for incorporation ...
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(2012-03-25)Department: ReligionGod invites us to share in holy communion in the whole of life. Holy communion is the feast of wholly charitable life together through which we participate in the holy nature and work of God’s perfect love. The problem ...
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(2017-03-20)Department: Community Research and ActionThis study investigates the case of an urban core neighborhood of Nashville, Tennessee, where rapid neighborhood changes in terms of the cultural, demographic, and built environments have prompted tensions between residents ...
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(2023-05-09)Department: MathematicsWe prove that the time of classical existence of smooth solutions to the relativistic Euler equations can be bounded from below in terms of norms that measure the ``(sound) wave-part" of the data in a low-regularity Sobolev ...
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(2020-08-20)Department: Biological SciencesThe endomembrane system describes the series of organelles and membrane-bound structures within which proteins are synthesized, packaged, and transported to various locations within the cell or are secreted from the plasma ...
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(2018-04-11)Department: PathologyThe family of ribosomal S6 Ser/Thr protein kinases (RSK) controls proliferation, viability and motility and, therefore, contributes to the etiology of numerous cancers, including breast. We found that RSK2 is an obligate ...
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Rural School Staff Roles in Career Development for Students with Disabilities: A Mixed Methods Study (2022-03-22)Department: Special EducationThe ways in which high schools allocate their staffing and assign individual roles related to career development are pertinent to students with and without disabilities accessing career preparation that equips them for ...
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(2015-11-12)Department: HistoryIn the early 1990s, the Russian intelligentsia encountered multiple new incentives in all realms: an ongoing democratic project with its opportunities for an open political activism, capitalism which mesmerized with easy ...
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(2005-09-09)Department: PathologyBifunctional alkylating agents that cause DNA cross-linking are implicated in the pathogenesis of myelodysplastic syndrome (MDS) and MDS related acute myeloid leukemia (MDR-AML). Therefore, characterizing hematopoietic ...
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(2021-05-12)Department: Chemical & Physical BiologyTranscranial focused ultrasound (FUS) is being studied for a number of research and clinical applications in the brain. Transcranial FUS is able to generate bioeffects with minimal invasiveness on a millimeter-scale. It ...