RSS 1.0Research reports
Recent Submissions
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(Journal of Infectious Diseases, 2020-03-01)Background. Multiple factors influence the human immunodeficiency virus (HIV) antibody response produced during natural infection, leading to responses that can vary in specificity, strength, and breadth. Methods. People ...
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(Allergy, 2020-02)Background The epithelial cell-derived danger signal mediators thymic stromal lymphopoietin (TSLP) and IL-33 are consistently associated with adaptive Th2 immune responses in asthma. In addition, TSLP and IL-33 synergistically ...
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(Antioxidants, 2020-01)Gastric cancer is the third main cause of cancerous tumors in humans in Chile. It is well-accepted that a diet rich in antioxidant plants could help in fighting cancer. Blueberry is a fruit crop with a high content of ...
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(Open Forum Infectious Diseases, 2019-11)Background. Loiasis is mostly considered a relatively benign infection when compared with other filarial and parasitic diseases, with Calabar swellings and eyeworm being the most common signs. Yet, there are numerous reports ...
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(Open Forum Infectiouis Diseases, 2019-12)Background. Community-acquired pneumonia (CAP) is the leading cause of death in children. Identification of reliable bio-markers offers the potential to develop a severity quantitative score to assist in clinical decision-making ...
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(Open Forum Infectious Diseases, 2019-07)Background. The US National Viral Hepatitis Action Plan depends on additional providers to expand hepatitis C virus (HCV) treatment capacity in order to achieve elimination goals. Clinical pharmacists manage treatment and ...
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(2019-07)Background. Rates of influenza hospitalizations differ by age, but few data are available regarding differences in laboratory-confirmed rates among adults aged >= 65 years. Methods. We evaluated age-related differences ...
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(Clinical Infectiouis Diseases, 2020-01-01)Background. Previous reports suggested that US methicillin-resistant Staphylococcus aureus (MRSA) strain epidemiology has changed since the rise of USA300 MRSA. We describe invasive MRSA trends by strain type. Methods. ...
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(Journal of the International AIDS Society, 2019-12)Introduction Identification of persons living with human immunodeficiency virus (HIV)-associated tuberculosis (TB) at increased risk for unfavourable TB outcomes would inform efforts to improve such outcomes. We sought to ...
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Temporal changes in ART initiation in adults with high CD4 counts in Latin America: a cohort study (Journal of the International AIDS Society, 2019-12)Introduction In 2013, the World Health Organization (WHO) recommended initiating combination ART (cART) in all adults with HIV and CD4+ lymphocyte counts (CD4) <500 cells/mm(3). In 2015, this was updated to recommend cART ...
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(JAIDS- Journal of Acquired Immune Deficiency Syndromes, 2019-03-01)Background: An increasing number of HIV-positive individuals now start antiretroviral therapy (ART) with high CD4 cell counts. We investigated whether this makes restoration of CD4 and CD8 cell counts and the CD4: CD8 ratio ...
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(Journal for Immunotherapy of Cancer, 2019-08-14)Background Prostate cancer is poorly responsive to immune checkpoint inhibition, yet a combination with radiotherapy may enhance the immune response. In this study, we combined radiotherapy with immune checkpoint inhibition ...
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(Human Vaccines & Immunotherapeutics, 2019-08-03)Objective: The primary aim of this study is to assess and characterize correlates of human papillomavirus (HPV) vaccine series completion among young adult women evaluated by gynecological (GYN) providers at a single ...
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(Metabolites, 2019-08)Renal cell carcinoma (RCC) is a heterogeneous malignancy which often develops and progresses asymptomatically. Benign oncocytomas are morphologically similar to malignant chromophobe RCC and distinguishing between these ...
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(MBIO, 2019-07)Phylosymbiosis is defined as microbial community relationships that recapitulate the phylogeny of hosts. As evidence for phylosymbiosis rapidly accumulates in different vertebrate and invertebrate holobionts, a central ...
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(Frontiers in Immunology, 2019-08-13)Multiple effector layers in the immune system ensure an optimal temporal and spatial distribution of immune defense. Cytotoxic innate lymphoid natural killers (NK) and adaptive CD8(+) T lymphocytes (CTL) interact to elicit ...
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(The Journal of Infectious Diseases, 2019-08-01)Metabolic complications relating to complex effects of viral and immune-mediated mechanisms are now a focus of clinical care among persons living with human immunodeficiency virus (PLHIV), and obesity is emerging as a ...
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(Scientific Reports, 2019-07-16)As a class, 'BET' inhibitors disrupt binding of bromodomain and extra-terminal motif (BET) proteins, BRD2, BRD3, BRD4 and BRDT, to acetylated histones preventing recruitment of RNA polymerase 2 to enhancers and promoters, ...
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(Frontiers in Bioengineering and Biotechnology, 2019-09-20)The extensive application of engineered nanomaterial (ENM) in various fields increases the possibilities of human exposure, thus imposing a huge risk of nanotoxicity. Hence, there is an urgent need for a detailed risk ...
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(Frontiers in Immunology, 2019-09-25)Our previous studies of protective immunity and pathology against blood stage malaria parasites have shown that not only CD4(+) T cells, but also CD8(+) T cells and macrophages, are important for host defense against blood ...