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Bone Fracture Acute Phase Response—A Unifying Theory of Fracture Repair: Clinical and Scientific Implications
(2018-12-29)
Bone fractures create five problems that must be resolved: bleeding, risk of infection, hypoxia, disproportionate strain, and inability to bear weight. There have been enormous advancements in our understanding of the ...
Autologous Chondrocyte Grafting Promotes Bone Formation in the Posterolateral Spine
(2018-03-23)
Pseudarthrosis following spinal fusion remains problematic despite modern surgical and grafting techniques. In surgical spinal fusion, new bone forms via intramembranous and endochondral ossification, with endochondral ...
Unexpected Timely Fracture Union in Matrix Metalloproteinase 9 Deficient Mice
(2018-05-31)
Immediately following a fracture, a fibrin laden hematoma is formed to prevent bleeding and infection. Subsequently, the organized removal of fibrin, via the protease plasmin, is essential to permit fracture repair through ...
Novel Preclinical Murine Model of Trauma-Induced Elbow Stiffness
(2018-09-18)
Peri-articular injury may result in functional deficits and pain. In particular, post-traumatic elbow stiffness is a debilitating condition, precluding patients from performing activities of daily living. As such, clinicians ...