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Viral flight data recorder for systems biology applications
(Vanderbilt University, 2008-08-13)
The paper briefly describes the construction of self organizing nanoparticles that can be designed to detect and record arbitrary intracellular events. The basic design captures nucleic acids. The design utilizes a single ...
Next-generation quantitative measurements to validate a model for yeast nitrogen catabolite repression in Saccharomyces cerevisiae
(Vanderbilt UniversityVanderbilt University, 2007-02-12)
Our work is motivated by the desire to quantitatively measure biological dynamical systems. Our agenda is to describe and understand emergent behavior and to explain the observed super robustness of biological dynamics. ...
Age distribution formulas for budding yeast
(Vanderbilt University, 2008-08-05)
Yeast are an important eukaryotic model system in the study of aging.
Replicative age in budding yeast can be quantitatively determined by visualizing chitanous bud scars.
The dynamics of the process of growth and division ...
Molecular Seismology: An inverse problem in nanobiology.
(Vanderbilt University, 2006-09-12)
The density profile of an elastic fiber like DNA will change in space and time as
ligands associate with it. This observation affords a new direction in single molecule
studies provided that density profiles can be ...