Search
Now showing items 1-10 of 13
The Brickyard in 2020
(2020)
The authors of this essay (David Furbish, Douglas Jerolmack and Rachel Glade) offer an updated view of the state of affairs in the brickyard described in B. K. Forscher’s popular 1963 allegorical letter to Science, “Chaos ...
Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy
(Cell Reports, 2020-02-11)
The reliance of many cancers on aerobic glycolysis has stimulated efforts to develop lactate dehydrogenase (LDH) inhibitors. However, despite significant efforts, LDH inhibitors (LDHi) with sufficient specificity and in ...
The Young Brickmakers
(2020)
In 2020, a young brickmaker (Kelsea Best) provides an update to B. K. Forscher's 1963 vision of the state of the scientific endeavor as a brickyard. As the brickyard becomes ever more chaotic, this essay calls on young ...
GPED Newsletter, Spring 2020
(2020-05-01)
Dark Matter benchmark models for early LHC Run-2 Searches: Report of the ATLAS/CMS Dark Matter Forum
(Physics of the Dark Universe, 2020-01)
This document is the final report of the ATLAS-CMS Dark Matter Forum, a forum organized by the ATLAS and CMS collaborations with the participation of experts on theories of Dark Matter, to select a minimal basis set of ...
Efficacy of virtual and asynchronous teaching of computer-assisted diagnosis of genetic diseases seen in clinics
(Wiley, 2021-12-11)
We studied if clinicians could gain sufficient working knowledge of a computer-assisted diagnostic decision support system (DDSS) (SimulConsult), to make differential diagnoses (DDx) of genetic disorders. We hypothesized ...
First Pass Effect in Patients Treated With the Trevo Stent-Retriever: A TRACK Registry Study Analysis
(Frontiers in Neurology, 2020-02-18)
Background and Objective: The first pass effect (FPE; achieving complete recanalization with a single thrombectomy device pass) has been shown to be associated with higher rates of good clinical outcomes in patients with ...
Rarefied particle motions on hillslopes: 2. Analysis (Supplementary Material)
(2020)
We conducted two sets of experiments. The first set was aimed at demonstrating the basis for treating the proportion of energy extraction, βx, as a random variable. In the second set of experiments we launched particles ...
Migdal effect and photon bremsstrahlung in effective field theories of dark matter direct detection and coherent elastic neutrino-nucleus scattering
(Physical Review D, 2020-01-22)
Dark matter direct detection experiments have limited sensitivity to light dark matter (below a few GeV), due to the challenges of lowering energy thresholds for the detection of nuclear recoil to below O(keV). While ...
Incumbent-led transitions and civil society: Autonomous vehicle policy and consumer organizations in the United States
(Technological Forecasting and Social Change, 2020-02)
The transition to connected and autonomous (or automated) vehicles (CAVs) in the United States is used to explore the role of civil society in the acceleration and deceleration of sociotechnical transitions. This is an ...