Browsing by Author "M. Shane Hutson"
Now showing items 1-20 of 21
-
Werdich, Andreas Augustinus (2006-04-05)Department: PhysicsThe dissertation describes the design and application of the Nanophysiometer, a microfluidic network that is combined with a thin film microelectrode array to study force – excitation coupling in single cardiac myocytes. ...
-
Mao, Qingqing (2015-07-20)Department: PhysicsIn this dissertation I present several different but related analyses of structure on both Galactic and extragalactic scales. I first investigate whether measurements of the moments of large-scale structure can yield ...
-
Auner, Alexander William (2018-09-20)Department: PhysicsThis work applies novel inverse modeling techniques to both chemical kinetics in lab-on-chip devices and cell mechanics in developing Drosophila embryos. The aim is to describe these systems quantitatively; to compare ...
-
Yirdaw, Robel Birru (2012-07-11)Department: PhysicsProteins, as intrinsically flexible molecules, exhibit internal motions at equilibrium. In general, the internal motions consist of changes in the three dimensional coordinates of the constituent atoms. These motions are ...
-
Jarvis, Jonathan Daniel (2009-03-12)Department: PhysicsThe primary purpose of this thesis is to detail recent progress in the development of high-brightness cathodes for use in beam driven radiation sources. In particular, diamond field-emitter arrays (DFEA) are discussed and ...
-
McDonald, Benjamin Seth (2010-04-12)Department: PhysicsSiliSPECT, a multi-pinhole, multi-detector SPECT system, was designed to image targeted regions of rodents at sub-300 micron resolution with stationary data acquisition. High spatial resolution is achieved with thick silicon ...
-
Shannon, Erica Kristine (2017-09-14)Department: Cell and Developmental BiologyIn normal epithelial wound repair, cells across an epithelial sheet begin a coordinated process of re-epithelialization within minutes of wounding. These coordinated behaviors are driven by a calcium wave, a rise in ...
-
Ramsey, Marc Christopher (2013-07-26)Department: Mechanical EngineeringThe collapse of a spherical cavity in liquid can focus energy in space and time, generating extreme thermodynamic states and emitting light and a strong shock wave. Such events, generally at the micro-scale, are of interest ...
-
Gai, Lili (2014-05-27)Department: Chemical EngineeringPhase transitions (i.e. transitions from one state to another) play a crucial role in most natural processes, as well as industrial operations such as evaporation. Molecular simulation has emerged as an important tool for ...
-
Kamai, Brittany Lehua (2016-07-24)Department: PhysicsA new ground-based detector, the Fermilab Holometer, has extended the accessible gravitational wave frequency range from kHz up to MHz. At these higher frequencies, exotic sources that were produced shortly after the Big ...
-
Lynch, Holley Ellen (2012-12-11)Department: PhysicsLiving tissues are active, non-linear viscoelastic materials that move drastically, often in concert, during embryogenesis. In many cases, the mechanics of this motion remain unknown. Using a combination of laser ...
-
Kraft, Lewis James (2014-05-27)Department: Chemical and Physical BiologyThe ubiquitin-like protein LC3 is a central component of the autophagy pathway where it functions in autophagosome formation and cargo selection. LC3 has an extensive network of interacting proteins, but little is known ...
-
Mashburn, David Nicholas (2015-04-02)Department: PhysicsMapping the forces responsible for morphogenetic movements in embryonic Drosophila melanogaster, or the fruit fly, is the focus of this thesis, specifically studying cellular pulsations and laser ablation wounds in the ...
-
Crescentini, Tiffany Marie (2019-03-25)Department: ChemistryPolyurethane (PU) di-block copolymers are one of the most versatile polymeric materials, commonly manufactured in the form of flexible and rigid foams, thermoplastics, thermosets, coatings, adhesives, sealants, and elastomers. ...
-
Holcomb, Mark Raymond (2007-05-30)Department: PhysicsOver 300,000 deaths in the United States each year are caused by sudden cardiac death. The most common cause of sudden cardiac death is ventricular fibrillation. Once initiated, ventricular fibrillation in humans almost ...
-
Crews, Sarah Michelle (2015-07-07)Department: PhysicsEnvironmental perturbations can disrupt development by altering both the molecular dynamics as well as tissue- and cell-level mechanics. Specifically, a heat shock administered in early Drosophila embryogenesis can result ...
-
Denton, Peter Bennert (2016-07-23)Department: PhysicsThis thesis covers two distinct topics: integral dispersion relations (IDRs) and ultra high energy cosmic ray (UHECR) anisotropy. Many models of electroweak symmetry breaking predict new physics scales near LHC energies. ...
-
Xu, Junkai (2007-09-13)Department: PhysicsMicrocalorimetry is an established technique in the biological sciences for determining energy generation and consumption. With recent developments in microfabrication techniques, nanocalorimeters or even picocalorimeters ...
-
McCleery, Winston Tyler (2016-04-06)Department: PhysicsBiomechanical analysis of the developing Drosophila embryo has historically focused on the role of individual cells. Cells translate genetic information into protein machinery that is capable of generating forces. With ...
-
Cogswell, Bernadette Kafwimbi (2014-10-28)Department: PhysicsWe conducted an updated global analysis of neutrino oscillation data using alternative bounds on the mixing angle theta-13 to determine the best fit mixing angles theta-13 and theta-23, the mass- squared difference ∆m_32^2, ...