Browsing Electronic Theses and Dissertations by Author "E. Duco Jansen"
Now showing items 1-20 of 30
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Paras, Constantine A (2012-04-06)Department: Biomedical EngineeringA major challenge in endocrine surgery is the intraoperative identification of parathyroid during both thyroid and parathyroid surgery. Current localization techniques are mostly preoperative and are imprecise. Optical ...
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Ayala, Oscar Daniel (2019-04-09)Department: Biomedical EngineeringOtitis media (OM), an inflammatory disease of the middle ear, is the most frequent cause of physician visits and prescription of antibiotics for children. Current methods to diagnose OM rely on varying symptoms and visual ...
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Duke, Austin Robert (2009-04-20)Department: Biomedical EngineeringThe recent development of low-intensity, pulsed infrared light for neural activation has provided a new nerve stimulation modality that avoids the limitations of traditional electrical methods such as the necessity of ...
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Vargis, Elizabeth Ann (2012-02-28)Department: Biomedical EngineeringRaman spectroscopy is an extremely sensitive technique that has been used by many research groups to differentiate between normal and abnormal changes in biological samples. Previous results have shown that when Raman ...
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Smith, Ralph Adam (2006-02-06)Department: Biomedical EngineeringSelective targeting of damaged or diseased cells is a concept with great potential to revolutionize the efficacy of systemically administered agents. Successful targeting preferentially delivers imaging agents and/or ...
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Faley, Shannon Leigh (2007-08-02)Department: Biomedical EngineeringT cells occupy a central role in cell-mediated immunity and as such, deciphering the signaling events that govern T cell activity is critical in fully understanding the adaptive immune response. Current immunologic ...
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McWade, Melanie Ann (2016-04-15)Department: Biomedical EngineeringThe inability to identify the parathyroid glands is a significant challenge during endocrine procedures. Successful parathyroid and thyroid surgeries require careful resection of diseased tissue and preservation of normal ...
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Patil, Chetan Appasaheb (2009-12-23)Department: Biomedical EngineeringSkin cancer is the most common cancer in the United States, with an incidence rate that continues to rise. Fortunately, it can be highly curable if detected at an early stage. Best clinical practices require physicians to ...
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Lapierre-Landry, Maryse (2018-08-20)Department: Biomedical EngineeringThere is a need for molecular imaging techniques in the eye to better understand disease progression, identify early disease markers, and evaluate new treatment options. Optical coherence tomography (OCT) provides high ...
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Pence, Isaac James (2016-12-06)Department: Biomedical EngineeringInflammatory bowel disease (IBD), comprised of Crohn’s disease and ulcerative colitis, is a complex autoimmune condition characterized by periods of disease flare and remission that seriously impact patient quality of life. ...
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Makowski, Alexander James (2014-11-18)Department: Biomedical EngineeringThe age-related risk of skeletal fracture is a significant problem in modern medicine, such that both hip fracture and osteoporotic fracture are listed in the World Health Organization top 12 sources of disease burden, ...
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Uhlhorn, Stephen R. (2003-02-20)Department: Biomedical EngineeringThe Vanderbilt University Free Electron Laser (FEL) is a tunable source of pulsed infrared radiation with pulse characteristics unlike those of most laser systems. A primary objective of the research presented in this ...
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Virostko, John Michael (2006-12-01)Department: Biomedical EngineeringThe islets of Langerhans play a central role in maintenance of glucose homeostasis. Apoptosis of the insulin-producing beta cells of the islet leads to diabetes mellitus. The ability to non-invasively image or assess the ...
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In Vivo Raman Spectroscopic Analysis of HSP70 and Laser Preconditioning in Murine Incisional Wounds Makowski, Alexander James (2010-04-16)Department: Biomedical EngineeringLaser preconditioning augments incisional wound healing by reducing scar tissue and increasing maximum tensile load of the healed wound. Under the hypothesis that HSP70 plays an active role in reported results and to better ...
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Gault, Melanie Ann (2011-08-08)Department: Biomedical EngineeringInfrared neural stimulation (INS) has been shown to induce neural activity with spatial selectivity without inducing a stimulation artifact or necessitating tissue contact. Most experiments with this technology have been ...
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Cayce, Jonathan Matthew (2008-05-05)Department: Biomedical EngineeringNeural stimulation using infrared light has recently been characterized as a novel method to stimulate peripheral nerves without touching, causing damage, or inducing an electrical stimulation artifact. Infrared neural ...
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Leveraging the Effect of Block Width during Infrared Neural Inhibition to Reduce Peak Temperatures Ford, Jeremy Berlin (2017-08-08)Department: Biomedical EngineeringChronic pain has a diverse set of causes and can manifest in many forms. Often times the pain becomes no longer a symptom but a disease itself, necessitating treatments which rely on direct control of neurons. Infrared ...
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Gebhart, Steven Charles (2006-12-13)Department: Biomedical EngineeringCurrent brain tumor localization methods demonstrate limited ability to discriminate between normal brain and infiltrating tumor margins, resulting in complete tumor resection in less than 20% of glioma patients. Combined ...
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Ganguly, Mohit (2019-06-17)Department: Biomedical EngineeringInfrared laser (IR) irradiation has been shown to block action potential generation and propagation in both mammalian and non-mammalian nerves. This effect has been shown to be reversible, spatially precise, and appears ...
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Dygert, Nicole Leigh (2008-08-26)Department: Interdisciplinary Materials ScienceA new deposition technique for high performance polymer films, resonant infrared laser ablation (RIR-LA) is presented. Ultraviolet laser deposition techniques have been shown to cause decomposition and depolymerization ...