RSS 1.0Electronic Theses and Dissertations
Electronic theses and dissertations of masters and doctoral students submitted to the Graduate School.
Authors retain copyright to their works.
Recent Submissions
-
(2023-01-30)Department: BiochemistryGenetic models suggested that SMARCA5 was required for DNA templated events including transcription, DNA replication and DNA repair. We engineered a degron tag into the endogenous alleles of SMARCA5, a catalytic component ...
-
(2022-11-22)Department: BiochemistryGenotoxic agents can cause nascent strand degradation (NSD) and fork reversal during DNA replication. NSD and fork reversal are crucial biochemical mechanisms that maintain genome stability and they are frequently exploited ...
-
(2022-11-22)Department: NeuroscienceAutism has long been considered an empathy related condition, yet empirical evidence supporting this claim has been inconclusive. While most cognitive empathy assessments suggest a decreased capacity for emotion recognition, ...
-
(2022-12-08)Department: Chemical & Physical BiologyCholesterol is one of the major lipid components of the plasma membrane in all mammalian cells. It has been shown to modulate membrane fluidity, assembly, organization, and dynamics and alter integral membrane protein (IMP) ...
-
(2022-11-18)Department: BiostatisticsIn phase 1 clinical trials, dose escalation is an iterative process whereby a maximum tolerated dose (MTD) is identified for subsequent testing. Patients are treated with escalating dose levels to determine which may result ...
-
(2022-11-18)Department: Earth & Environmental SciencesAccording to the Habitat Amount Hypothesis, the total amount of habitat in a landscape should be the main determinant for species richness, but how does the quality of the habitat and the surrounding landcovers (termed the ...
-
(2022-11-17)Department: Computer SciencePublic perception plays an increasingly important role in policy decision-making and resource allocation. Conventional studies on public perception have mainly relied upon formal surveys, which are limited in their ability ...
-
(2022-11-16)Department: Chemical & Physical BiologyMy graduate work has primarily focused on using computational methods applied to early-stage drug discovery. This has involved method development projects that aim to improve existing computational methods, while also ...
-
(2022-11-19)Department: Biomedical EngineeringThe inflammatory response within the brain and spinal cord is a key biological response to disease, infection, and injury. Chronic pain and blast-induced traumatic brain injury (bTBI) are negatively impacted by the role ...
-
(2022-11-16)Department: SociologyScholars have recently examined the cost of activism for activists, paying particular attention to burnout experiences in social justice spaces, yet we still know very little about the role of White supremacy to burnout ...
-
(2022-11-18)Department: Biomedical EngineeringInfrared neural stimulation (INS) is a label-free method that uses infrared light to excite neural tissue. INS has high spatial specificity and artifact-free stimulation, offering distinct benefits compared to traditional ...
-
(2022-11-17)Department: Cell & Developmental BiologyThe overarching goal of my thesis work is to better understand the transcriptional regulation and functions of Sox17 during early development. To start unveiling the complex molecular mechanisms that modulate Sox17 expression, ...
-
(2022-11-22)Department: Special EducationIn progress
-
(2022-11-17)Department: Computer ScienceIn the last few decades, with the introduction of machine learning, research on the design and monitoring of civil structures and mechanical systems has evolved into a new era. One of the main challenges in developing ...
-
(2022-11-16)Department: Electrical EngineeringTotal-ionizing-dose (TID) effects on 3D sequentially integrated (3DSI) FDSOI MOSFETs and ring oscillator (RO) circuits. Firstly, bottom-layer devices show significant charge trapping, transconductance degradation, and ...
-
(2022-12-09)Department: Biomedical InformaticsSuicide is a significant threat to public health. In the United States, 47,500 people died from suicide in 2019, a 10-year increase of 30%. Informaticians studying suicide are working on improved ways to analyze suicide ...
-
(2022-11-19)Department: Interdisciplinary Materials ScienceThe random thermal motion of charges in a material results in emitted radiation that is spatially and temporally incoherent. The spatial incoherence corresponds to the lack of correlation between the oscillating dipoles ...
-
(2022-11-11)Department: BiostatisticsLarge clinical and epidemiological studies allow researchers to study drug and exposure effects across populations and increase the chance of observing rare events. However, with large studies come increased data volume, ...
-
(2022-11-16)Department: ChemistryOne of the most commonly used chemotherapeutic regimens is the adjuvant combination therapy called Adriamycin/Cyclophosphamide (AC) Chemotherapy. These two drugs are understood to work separately to induce an additive ...
-
(2022-11-18)Department: Computer ScienceMachine learning with deep neural networks has been ubiquitous in solving various real-world problems with distinct human inputs, such as images, natural language, speech, and motion. As deep learning technology transitions ...