Browsing Electronic Theses and Dissertations by Title
Now showing items 3674-3693 of 7147
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(2010-04-15)Department: PharmacologyMuscarinic acetylcholine receptors (mAChRs), specifically M1 and M4 subtypes, provide viable targets for the treatment of multiple central nervous system disorders. However, highly selective activators of either M1 or M4 ...
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(2023-07-17)Department: Pharmacologytbd
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(2023-07-17)Department: Pharmacologytbd
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(2011-08-03)Department: ChemistryThe focus of this work was to establish quantitative structure activity (QSAR, potency of allosteric modulators) and property (QSPR, carbon chemical shifts) relations for molecules with known structure and activity/property ...
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(2024-03-04)Department: Human GeneticsDevelopmental stuttering is a speech disorder characterized by disruption in the forward movement of speech. This disruption includes part-word and single-syllable repetitions, prolongations, and involuntary tension that ...
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(2019-05-23)Department: Civil EngineeringEngineering systems following disruptive events usually experience abrupt performance degradation over time. How to mitigate the disastrous effect of unanticipated events and restore the performance of the system to the ...
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(2022-08-24)Department: AstrophysicsUnderstanding how structures in the universe form and grow under the influence of gravity is fundamental to our understanding of how the universe we observe came to be. However, simulations of dark matter, which are one ...
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Machine Learning Based Prediction and Classification of Properties of Engineered Composite Materials (2020-04-03)Department: Civil EngineeringIn an engineered composite material, the behavior of different phases and their interactions determine the response of the material as a whole. Data-driven machine learning techniques have emerged as a promising tool for ...
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(2023-11-16)Department: Computer ScienceClonal Hematopoiesis of Indeterminate Potential (CHIP) is characterized by genetic mutations within blood-forming stem cells, leading to the emergence of mutated blood cell populations. Associated with elevated risks of ...
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(2019-03-18)Department: Electrical EngineeringCochlear Implants (CIs) are neural prosthetics that are used to treat patients with profound hearing loss. In surgery, an electrode array is threaded into the cochlea. Post-operatively, the CI needs to be programmed. In ...
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(2021-08-09)Department: Electrical EngineeringThis dissertation introduces several innovative machine learning-based techniques for medical image registration and segmentation and a technique for patient-customized placement of cochlear implant electrodes. We have ...
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(2016-09-15)Department: Electrical EngineeringAutism Spectrum Disorder (ASD) is a neuro-developmental disorder with a high prevalence rate of 1 in 68 children in the U.S. Human-Machine Interaction (HMI) is being continuously explored as a potential efficacious ...
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(2022-06-20)Department: Biological SciencesRare genetic diseases affect more than 300 million people around the world; however, the causative genes and variants have not been identified for most. The Undiagnosed Diseases Network (UDN) was established to help elucidate ...
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(2012-04-10)Department: Leadership and Policy StudiesRace to the Top is a new policy lever in the struggle for authority in educational governance among various levels of government, and it provides an opportunity to examine the state-level policymaking context. Tennessee ...
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(2015-07-16)Department: Molecular Physiology and BiophysicsReduced pancreatic β cell mass is a hallmark of diabetes, which makes the ability to increase or restore β cell mass a major therapeutic goal. While testing the hypothesis that increased endothelial cell signaling would ...
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(2007-12-13)Department: SpanishThis study examines the comic vision of Miguel de Cervantes as manifested in his masterpiece, Don Quixote de la Mancha. Employing theories stemming principally from Mikhail Bakhtin and Michel Foucault, I look at how Cervantes ...
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Magical Objects in Victorian Literature: Enchantment, Narrative Imagination, and the Power of Things (2015-07-27)Department: EnglishThis dissertation examines the representation of magical objects in Victorian literature. The Victorian period is often characterized as a time of increased secularity. Scientists, sociologists, and anthropologists in the ...
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(2023-11-17)Department: Earth & Environmental SciencesThe Ora Ignimbrite (~275 Ma) is a crystal-rich (~40%), heterogeneous, supereruption-sized (~1,300 km3) rhyolite in northern Italy and the final eruptive product of the Athesian Volcanic Group (289 - 274 Ma), the largest ...
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(2023-11-17)Department: Earth & Environmental SciencesThe Ora Ignimbrite (~275 Ma) is a crystal-rich (~40%), heterogeneous, supereruption-sized (~1,300 km3) rhyolite in northern Italy and the final eruptive product of the Athesian Volcanic Group (289 - 274 Ma), the largest ...
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(2023-11-17)Department: Earth & Environmental SciencesThe Ora Ignimbrite (~275 Ma) is a crystal-rich (~40%), heterogeneous, supereruption-sized (~1,300 km3) rhyolite in northern Italy and the final eruptive product of the Athesian Volcanic Group (289 - 274 Ma), the largest ...