Cardiovascular Medicine: Recent submissions
Now showing items 1-20 of 24
-
(Molecular Metabolism, 2023-01-13)Objective: Oxidative stress contributes to the development of insulin resistance (IR) and atherosclerosis. Peroxidation of lipids produces reactive dicarbonyls such as Isolevuglandins (IsoLG) and malondialdehyde (MDA) that ...
-
(Journal of the American Heart Association, 2019-12-03)Background The New York Heart Association (NYHA) classification has served as a fundamental tool for risk stratification of heart failure (HF) and determines clinical trial eligibility and candidacy for drugs and devices. ...
-
(2020-01-07)Background In infants with ductal-dependent pulmonary blood flow, the impact of palliation strategy on interstage growth and feeding regimen is unknown. Methods and Results This was a retrospective multicenter ...
-
(JACC-Heart Failure, 2020-03)Whereas multiple national, international, and trial registries for heart failure have been created, international standards for clinical assessment and outcome measurement do not currently exist. The working group's objective ...
-
(Journal of the American Heart Association, 2020-01-21)
-
(Pulmonary Circulation, 2020-01)Pulmonary arterial hypertension (PAH) is a sexually dimorphic disease that for unknown reasons affects women more than men. The role of estrogens, both endogenous and exogenous, and reproductive factors in this female ...
-
(2019-12-17)Background Data are limited on use patterns of low-dose aspirin and its role for primary prevention of cardiovascular disease (CVD) in different racial and ethnic groups. Methods and Results Overall, 65 231 ...
-
(JRSM Cardiovascular Disease, 2020-02)Purpose Chronic thromboembolic pulmonary hypertension is characterized by incomplete thrombus resolution following acute pulmonary embolism, leading to pulmonary hypertension and right ventricular dysfunction. Conditions ...
-
(Hypertension, 2020-02)While hypertension and inflammation are physiologically inter-related, the effect of therapies that specifically target inflammation on blood pressure is uncertain. The recent CANTOS (Canakinumab Anti-inflammatory Thrombosis ...
-
2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias (Heart Rhythm, 2020-01)Ventricular arrhythmias are an important cause of morbidity and mortality and come in a variety of forms, from single premature ventricular complexes to sustained ventricular tachycardia and fibrillation. Rapid developments ...
-
(Journal of the American Heart Association, 2019-05-07)Background-PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitors effectively lower LDL (low-density lipoprotein) cholesterol and have been shown to reduce cardiovascular outcomes in high-risk patients. We used ...
-
(Journal of the American Heart Association, 2019-06-04)Background-Elevated total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), triglycerides, and non-high-density lipoprotein cholesterol (non-HDL-C) and low high-density lipoprotein cholesterol (HDL-C) ...
-
(Journal of the American Heart Association, 2019-07-16)Background-Cardiovascular disease is a major cause of morbidity and mortality in children with chronic kidney disease. We sought to determine the prevalence of cardiovascular risk factors in children with glomerular disease ...
-
(Journal of the American Heart Association, 2019-08-06)Background-Subtle reductions in cardiac output relate to lower cerebral blood flow, especially in regions where Alzheimer's disease pathology first develops. Apolipoprotein E (APOE)-epsilon 4 is a genetic susceptibility ...
-
(Journal of the American Heart Association, 2019-06-18)
-
(Journal of the American Heart Association, 2019-03-19)Background-Prior studies relating proteomics markers to incident AF screened for limited numbers of proteins. Methods and Results-We performed proteomics assays among participants from the Framingham Heart Study Offspring ...
-
(Journal of the American Heart Association, 2019-08-20)Background-Duchenne muscular dystrophy (DMD) is an X-linked disease that causes progressive muscle weakness. Affected boys typically die from respiratory or cardiac failure. Golden retriever muscular dystrophy (GRMD) is ...
-
(Journal of the American Heart Association, 2019-08-20)Background-alpha Carboxyl terminus 1 (alpha CT1) is a 25-amino acid therapeutic peptide incorporating the zonula occludens-1 (ZO-1)-binding domain of connexin 43 (Cx43) that is currently in phase 3 clinical testing on ...
-
(Journal of the American Heart Association, 2019-09-23)Background-Identification of occult diastolic dysfunction often requires invasive right heart catheterization with provocative maneuvers such as fluid challenge. Non-invasive predictors of occult diastolic dysfunction have ...
-
(European Journal of Heart Failur, 2019-09)Current pharmacological therapies for heart failure with reduced ejection fraction are largely either repurposed anti-hypertensives that blunt overactivation of the neurohormonal system or diuretics that decrease congestion. ...