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Identification of a Pro-angiogenic Functional Role for FSP1-positive Fibroblast Subtype in Wound Healing
(NATURE COMMUNICATIONS, 2019-07-09)
Fibrosis accompanying wound healing can drive the failure of many different organs. Activated fibroblasts are the principal determinants of post-injury pathological fibrosis along with physiological repair, making them a ...
Modification of the Gastric Mucosal Microbiota by a Strain-Specific Helicobacter pylori Oncoprotein and Carcinogenic Histologic Phenotype
(MBIO, 2019-05)
Helicobacter pylori is the strongest risk factor for gastric adenocarcinoma; however, most infected individuals never develop this malignancy. Strain-specific microbial factors, such as the oncoprotein CagA, as well as ...
Obesity and Fat Metabolism in Human Immunodeficiency Virus-Infected Individuals: Immunopathogenic Mechanisms and Clinical Implications
(The Journal of Infectious Diseases, 2019-08-01)
Metabolic complications relating to complex effects of viral and immune-mediated mechanisms are now a focus of clinical care among persons living with human immunodeficiency virus (PLHIV), and obesity is emerging as a ...
Host Inflammatory Biomarkers of Disease Severity in Pediatric Community-Acquired Pneumonia: A Systematic Review and Meta-analysis
(Open Forum Infectiouis Diseases, 2019-12)
Background. Community-acquired pneumonia (CAP) is the leading cause of death in children. Identification of reliable bio-markers offers the potential to develop a severity quantitative score to assist in clinical decision-making ...