Browsing Research reports by Title
Now showing items 1-20 of 34
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(NATURE COMMUNICATIONS, 2019-07-10)TFF1, a secreted protein, plays an essential role in keeping the integrity of gastric mucosa and its barrier function. Loss of TFF1 expression in the TFF1-knockout (KO) mouse leads to a pro-inflammatory phenotype with a ...
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(2019-07)Background. Rates of influenza hospitalizations differ by age, but few data are available regarding differences in laboratory-confirmed rates among adults aged >= 65 years. Methods. We evaluated age-related differences ...
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(Molecules, 2022-12-09)Although 3-aminopropyl functionalized magnesium phyllosilicate nanoparticles (hereafter aminoclay nanoparticles, ACNs) are well-known nanomaterials employed as drug carriers, their effects on immune cells remain unclear. ...
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(Antioxidants, 2020-01)Gastric cancer is the third main cause of cancerous tumors in humans in Chile. It is well-accepted that a diet rich in antioxidant plants could help in fighting cancer. Blueberry is a fruit crop with a high content of ...
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(eLife, 2019-03-27)Immune activated T lymphocytes modulate the activity of key metabolic pathways to support the transcriptional reprograming and reshaping of cell proteomes that permits effector T cell differentiation. The present study ...
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(Open Forum Infectious Diseases, 2019-11)Background. Loiasis is mostly considered a relatively benign infection when compared with other filarial and parasitic diseases, with Calabar swellings and eyeworm being the most common signs. Yet, there are numerous reports ...
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(Acta Neuropathologica Communications, 2022-12-17)Background: This study examined neuropathological findings of patients who died following hospitalization in an intensive care unit with SARS-CoV-2.Methods: Data originate from 20 decedents who underwent brain autopsy ...
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(Frontiers in Immunology, 2019-08-13)Multiple effector layers in the immune system ensure an optimal temporal and spatial distribution of immune defense. Cytotoxic innate lymphoid natural killers (NK) and adaptive CD8(+) T lymphocytes (CTL) interact to elicit ...
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(Journal for Immunotherapy of Cancer, 2019-08-14)Background Prostate cancer is poorly responsive to immune checkpoint inhibition, yet a combination with radiotherapy may enhance the immune response. In this study, we combined radiotherapy with immune checkpoint inhibition ...
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(Research And Practice In Thrombosis And Haemostasis, 2022-10-11)
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(JAIDS- Journal of Acquired Immune Deficiency Syndromes, 2019-03-01)Background: An increasing number of HIV-positive individuals now start antiretroviral therapy (ART) with high CD4 cell counts. We investigated whether this makes restoration of CD4 and CD8 cell counts and the CD4: CD8 ratio ...
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(Journal of the International AIDS Society, 2019-12)Introduction Identification of persons living with human immunodeficiency virus (HIV)-associated tuberculosis (TB) at increased risk for unfavourable TB outcomes would inform efforts to improve such outcomes. We sought to ...
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(Frontiers in Bioengineering and Biotechnology, 2019-09-20)The extensive application of engineered nanomaterial (ENM) in various fields increases the possibilities of human exposure, thus imposing a huge risk of nanotoxicity. Hence, there is an urgent need for a detailed risk ...
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(Open Forum Infectious Diseases, 2019-07)Background. The US National Viral Hepatitis Action Plan depends on additional providers to expand hepatitis C virus (HCV) treatment capacity in order to achieve elimination goals. Clinical pharmacists manage treatment and ...
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(Frontiers in Immunology, 2019-09-25)Our previous studies of protective immunity and pathology against blood stage malaria parasites have shown that not only CD4(+) T cells, but also CD8(+) T cells and macrophages, are important for host defense against blood ...
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(Open Forum Infectiouis Diseases, 2019-12)Background. Community-acquired pneumonia (CAP) is the leading cause of death in children. Identification of reliable bio-markers offers the potential to develop a severity quantitative score to assist in clinical decision-making ...
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(Human Vaccines & Immunotherapeutics, 2019-08-03)Objective: The primary aim of this study is to assess and characterize correlates of human papillomavirus (HPV) vaccine series completion among young adult women evaluated by gynecological (GYN) providers at a single ...
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(NATURE COMMUNICATIONS, 2019-07-09)Fibrosis accompanying wound healing can drive the failure of many different organs. Activated fibroblasts are the principal determinants of post-injury pathological fibrosis along with physiological repair, making them a ...
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(FRONTIERS IN MICROBIOLOGY, 2019-07-23)Acinetobacter baumannii A118, a strain isolated from the blood of an infected patient, is naturally competent and unlike most clinical strains, is susceptible to a variety of different antibiotics including those usually ...
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(Cancer Iinformatics, 2019-04-16)The genome-wide identification of mutated genes is an important advance in our understanding of tumor biology, but several fundamental questions remain open. How do these genes act together to promote cancer development ...