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Ulcerative Colitis: Current and Emerging Treatment Strategies
(Journal of Clinical Medicine, 2020-01)
Historically, medical therapy for ulcerative colitis (UC) was limited to corticosteroids. Excitingly, over the past just 1-2 decades, the options for medical therapy have expanded and include biologics and small molecules, ...
BNST-insula structural connectivity in humans
(Neuroimage, 2020-04-15)
The bed nucleus of the stria terminalis (BNST) is emerging as a critical region in multiple psychiatric disorders including anxiety, PTSD, and alcohol and substance use disorders. In conjunction with growing knowledge of ...
Efficacy and safety of cap-assisted endoscopic mucosal resection of ileocecal valve polyps
(Endoscopy International Open, 2020-03)
Background and study aims Standard endoscopic mucosal resection (EMR) of ileocecal valve (ICV) polyps is challenging. Cap-assisted endoscopic mucosal resection (C-EMR) can be performed when polyps are not easily amenable ...
Specific chromatin landscapes and transcription factors couple breast cancer subtype with metastatic relapse to lung or brain
(BMC Medica Genomics, 2020-03-06)
Background Few somatic mutations have been linked to breast cancer metastasis, whereas transcriptomic differences among primary tumors correlate with incidence of metastasis, especially to the lungs and brain. However, the ...
Updated nomenclature of delirium and acute encephalopathy: statement of ten Societies
(Intensive Care Medicine, 2020-02)
Longitudinal Antibody Responses in People Who Inject Drugs Infected With Similar Human Immunodeficiency Virus Strains
(Journal of Infectious Diseases, 2020-03-01)
Background. Multiple factors influence the human immunodeficiency virus (HIV) antibody response produced during natural infection, leading to responses that can vary in specificity, strength, and breadth.
Methods. People ...
A review of published anticholinergic scales and measures and their applicability in database analyses
(Archives of Gerontogy and Geriatrics, 2020-03)
Background/objectives: Available metrics for characterizing cumulative anticholinergic exposure over time may not be well suited for use across all US data sources. In this review, the properties of existing anticholinergic ...
The 2019 Schizophrenia International Research Society Conference, 10-14 April, Orlando, Florida: A summary of topics and trends
(Psychiatry Research, 2020-02)
The Schizophrenia International Research Society (SIRS) recently held its first North American congress, which took place in Orlando, Florida from 10-14 April 2019. The overall theme of this year's congress was United in ...
A multifaceted investigation into molecular associations of chronic thromboembolic pulmonary hypertension pathogenesis
(JRSM Cardiovascular Disease, 2020-02)
Purpose
Chronic thromboembolic pulmonary hypertension is characterized by incomplete thrombus resolution following acute pulmonary embolism, leading to pulmonary hypertension and right ventricular dysfunction. Conditions ...
Median Nerve Variation: A Complete Spin before Terminal Branching
(Journal of Brachial Plexus and Periheral Nerve Injury, 2020-01)
Median nerve anatomy is of great interest to clinicians and scientists given the importance of this nerve and its association with diseases. A rare anatomical variant of the median nerve in the distal forearm and wrist was ...