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Measuring the health of medication process using an EHR data repository

dc.creatorBhatia, Haresh Lokumal
dc.date.accessioned2020-08-22T20:40:33Z
dc.date.available2017-08-06
dc.date.issued2015-08-06
dc.identifier.urihttps://etd.library.vanderbilt.edu/etd-07302015-120900
dc.identifier.urihttp://hdl.handle.net/1803/13747
dc.description.abstractDissertation under the direction of Dr. Christoph U. Lehmann Health care providers prescribe medications to treat disease or maintain health of their patients. In an inpatient environment, once a medication order has been issued a complex medication process must be successfully and error free navigated to assure delivery and administration of the medication. This process involves providers, pharmacists, pharmacy technicians, nurses, and nursing aids and can result in errors in dispensing, delivery, administration, and documentation. This project analyzed the medication process in a children’s hospital to develop new approaches and methodologies to determine the effectiveness of the medication process and to develop measures to monitor its health. The approach chosen to determine the “health” of the medication process for the pediatric patients at the Vanderbilt University Medical Center (VUMC) was threefold: 1. Assessment of the proportion of medications not administered to patients including truly missed doses (no administration record) and non-administered medications 2. Assessment of intervals from ordering to dispensing, scheduling, and administration of medications 3. Analysis of factors influencing non-administration and delays in administration Analysis of orders issued between July 1, 2010 and December 31, 2013 revealed a very small proportion (< 3%) of doses that were not administered. However, we observed that the non-administration of the ordered medication is associated with the corresponding Anatomical Therapeutic Chemical (ATC) class. The analysis of the schedule and administration times of the ordered medications with respect to the order type, required verification, unit, ATC class, and scheduled-hour provided greater insights including understanding of delays associated with peek demands (pharmacy) and shift changes (nurses). Incidentally, while analyzing the schedule and administration times, we observed noticeably better times for specific antimicrobials in one of the Neonatal ICUs (NICUs). Further inquiry revealed that the effect was due to a quality improvement effort initiated at this NICU. Conclusion: Ordering, dispensing, scheduling, and administration data are useful in determining the “health” of the medication process in a university children’s hospital. Further, this analysis independently can detect ongoing improvement efforts.
dc.format.mimetypeapplication/pdf
dc.subjectPediatric Inpatients
dc.subjectMissing Doses
dc.subjectMedication Compliance
dc.subjectQuality Improvement signals from EHR
dc.subjectTime to First Dose
dc.titleMeasuring the health of medication process using an EHR data repository
dc.typedissertation
dc.contributor.committeeMemberDr. Neal R. Patel
dc.contributor.committeeMemberDr. Catherine H. Ivory
dc.contributor.committeeMemberDr. Phillip W. Stewart
dc.contributor.committeeMemberDr. Kim M. Unertl
dc.type.materialtext
thesis.degree.namePHD
thesis.degree.leveldissertation
thesis.degree.disciplineBiomedical Informatics
thesis.degree.grantorVanderbilt University
local.embargo.terms2017-08-06
local.embargo.lift2017-08-06
dc.contributor.committeeChairDr. Christoph U. Lehmann


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