Viral flight data recorder for systems biology applications

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Vanderbilt University

Abstract

The paper briefly describes the construction of self organizing nanoparticles that can be designed to detect and record arbitrary intracellular events. The basic design captures nucleic acids. The design utilizes a single viral coat protein to nucleate a capsid if and only if a quantum of specific intracellular events occur.

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Intracellular event detection, Single molecule detection, Viral capsid assembly, Self organizing nanoparticles

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