Examining the Association Between Vigorous Physical Activity and Pregnancy-related Outcomes

dc.contributor.advisorHartmann, Katherine E.
dc.contributor.committeeChairVelez Edwards, Digna R.
dc.contributor.committeeMemberWu, Pengsheng
dc.contributor.committeeMemberLipworth, Loren P.
dc.creatorZhao, Sifang Kathy
dc.creator.orcid0000-0002-9019-2186
dc.date.accessioned2020-09-22T22:38:26Z
dc.date.created2020-06
dc.date.issued2020-06-03
dc.date.submittedJune 2020
dc.date.updated2020-09-22T22:38:26Z
dc.description.abstractPregnancy is an ideal time for positive lifestyle modifications, including sustaining physical activity behavior. However, medical association guidelines specifically avoid giving recommendations on the optimal frequency or amount of vigorous physical activity (VPA) for women planning or carrying a pregnancy. Due to limited literature, little is known about the risks and benefits of VPA on pregnancy-related outcomes, including time to pregnancy, miscarriage, and infant birthweight. Furthermore, the effects of various modes of VPA on pregnancy-related outcomes cannot be evaluated. This work examines the influence of cumulative VPA across modes using Right from the Start, a community-recruited cohort with over five thousand pregnant women from Southern United States. I found that VPA prior to conception, estimated using VPA during the first trimester, has no effect on time to pregnancy, regardless of women’s body mass index. I also found that cumulative VPA frequency and amount have no effect on miscarriage risk, adjusting for nausea and vomiting symptoms. While VPA frequency is not associated with infant birthweight, higher VPA amounts may be associated with increased birthweight. In summary, this work suggests women may continue levels of activity that are vigorous and contributes data on the safe upper limit for frequency and amount of physical activity immediately prior to and during early pregnancy.
dc.format.mimetypeapplication/pdf
dc.identifier.urihttp://hdl.handle.net/1803/16073
dc.language.isoen
dc.subjectVigorous physical activity
dc.subjectTime to pregnancy
dc.subjectMiscarriage
dc.subjectBirthweight
dc.subjectPregnancy
dc.subjectEpidemiology
dc.titleExamining the Association Between Vigorous Physical Activity and Pregnancy-related Outcomes
dc.typeThesis
dc.type.materialtext
local.embargo.lift2022-06-01
local.embargo.terms2022-06-01
thesis.degree.disciplineEpidemiology
thesis.degree.grantorVanderbilt University Graduate School
thesis.degree.levelDoctoral
thesis.degree.namePhD

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