Search
Now showing items 1-1 of 1
Point mutations in the PDX1 transactivation domain impair human beta-cell development and function
(Molecular Metabolism, 2019-06)
Objective: Hundreds of missense mutations in the coding region of PDX1 exist; however, if these mutations predispose to diabetes mellitus is unknown.
Methods: In this study, we screened a large cohort of subjects with ...