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Structural state recognition facilitates tip tracking of EB1 at growing microtubule ends
(eLIFE, 2019-09-03)
The microtubule binding protein EB1 specifically targets the growing ends of microtubules in cells, where EB1 facilitates the interactions of cellular proteins with microtubule plus-ends. Microtubule end targeting of EB1 ...
Microtubule minus-end stability is dictated by the tubulin off-rate
(Journal of Cell Biology, 2019-09)
Dynamic organization of microtubule minus ends is vital for the formation and maintenance of acentrosomal microtubule arrays. In vitro, both microtubule ends switch between phases of assembly and disassembly, a behavior ...