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Novel Preclinical Murine Model of Trauma-Induced Elbow Stiffness

dc.contributor.authorMoore-Lotridge, Stephanie N.
dc.contributor.authorOelsner, William K.
dc.contributor.authorIhejirika, Yael
dc.contributor.authorDesai, Mihir J.
dc.contributor.authorGebhart, Sandra S.
dc.contributor.authorSchoenecker, Jonathan G.
dc.date.accessioned2019-02-05T17:29:58Z
dc.date.available2019-02-05T17:29:58Z
dc.date.issued2018-09-18
dc.identifier.citationMoore-Lotridge, S. N., Oelsner, W. K., Ihejirika, Y., Desai, M. J., Gebhart, S. S., & Schoenecker, J. G. (2018). Novel preclinical murine model of trauma-induced elbow stiffness. Journal of Experimental Orthopaedics, 5(1), 36. https://doi.org/10.1186/s40634-018-0155-3en_US
dc.identifier.issn2197-1153
dc.identifier.other10.1186/s40634-018-0155-3
dc.identifier.urihttp://hdl.handle.net/1803/9377
dc.description.abstractPeri-articular injury may result in functional deficits and pain. In particular, post-traumatic elbow stiffness is a debilitating condition, precluding patients from performing activities of daily living. As such, clinicians and basic scientists alike, aim to develop novel therapeutic interventions to prevent and treat elbow stiffness; thereby reducing patient morbidity. Yet, there is a paucity of pre-clinical models of peri-articular stiffness, especially of the upper extremity, necessary to develop and test the efficacy of therapeutics. We set out to develop a pre-clinical murine model of elbow stiffness, resulting from soft tissue injury, with features characteristic of pathology observed in these patients.en_US
dc.language.isoen_USen_US
dc.subjectElbow Stiffnessen_US
dc.subjectMurine Modelen_US
dc.subjectPreclinical Modelen_US
dc.subjectElbow Traumaen_US
dc.subject.lcshOrthopaedicsen_US
dc.subject.lcshPlasminogenen_US
dc.subject.lcshPlasminen_US
dc.titleNovel Preclinical Murine Model of Trauma-Induced Elbow Stiffnessen_US
dc.typeArticleen_US
dcterms.rights© The Author(s). 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.en_US


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