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A Trans-Ethnic Genome-Wide Association Study of Uterine Fibroids
(Frontiers in Genetics, 2019-06-12)
Uterine fibroids affect up to 77% of women by menopause and account for up to $34 billion in healthcare costs each year. Although fibroid risk is heritable, genetic risk for fibroids is not well understood. We conducted a ...
Use of Genetic Variants Related to Antihypertensive Drugs to Inform on Efficacy and Side Effects
(Circulation, 2019-07-23)
Background: Drug effects can be investigated through natural variation in the genes for their protein targets. The present study aimed to use this approach to explore the potential side effects and repurposing potential ...