Browsing Vanderbilt University Medical Center by Author "Eischen, Christine M."

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    • Targeting MYC through WDR5 
      Thomas, Lance R.; Adams, Clare M.; Fesik, Stephen W.; Eischen, Christine M.; Tansey, William P. (Molecular & Cellular Oncology, 2020-03-03)
      The oncoprotein transcription factor MYC is overexpressed in most cancers and is responsible for hundreds of thousands of cancer deaths worldwide every year. MYC is also a highly validated - but currently undruggable - ...