Browsing Vanderbilt University Medical Center by Title
Now showing items 260-279 of 315
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(Pulmonary Circulation, 2020-01)Pulmonary arterial hypertension (PAH) is a sexually dimorphic disease that for unknown reasons affects women more than men. The role of estrogens, both endogenous and exogenous, and reproductive factors in this female ...
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(G3-GENES Genomes Genetics, 2019-08)Evolutionary changes in enhancers are widely associated with variation in human traits and diseases. However, studies comprehensively quantifying levels of selection on enhancers at multiple evolutionary periods during ...
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(2017-02-09)Background. Prior studies of pediatric musculoskeletal infection have suggested that methicillin-resistant Staphylococcus aureus (MRSA) infections result in worse outcomes compared with infections with methicillin-susceptible ...
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(Cell Death & Disease, 2023-01-16)Tumor growth, metastasis and therapeutic response are believed to be regulated by the tumor and its microenvironment (TME) in advanced renal cell carcinoma (RCC). However, the mechanisms underlying genomic, transcriptomic ...
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(Molecular Genetics & Genomic Medicine, 2019-09)Background Congenital hydrocephalus (CH) is a highly morbid disease that features enlarged brain ventricles and impaired cerebrospinal fluid homeostasis. Although early linkage or targeted sequencing studies in large ...
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(Brain Communications, 2022-12-17)Sleep is the preferential period when epileptic spike-wave discharges appear in human epileptic patients, including genetic epileptic seizures such as Dravet syndrome with multiple mutations including SCN1A mutation and ...
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(Magnetic Resonance Imaging, 2020-02)Purpose:: Magnetic resonance fingerprinting (MRF) is a state-of-the-art quantitative MRI technique with a computationally demanding reconstruction process, the accuracy of which depends on the accuracy of the signal model ...
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(Hepatology, 2019-08)Currently, the only approved hepatitis C virus (HCV) treatment for children aged <12 years is pegylated interferon plus ribavirin. In an open-label study, we evaluated the safety and efficacy of sofosbuvir plus ribavirin ...
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(Neuroimage-/Clinical, 2019)Abstract Purpose: This study aims to systematically evaluate the accuracy and precision of pool size ratio (PSR) measurements from quantitative magnetization transfer (qMT) acquisitions using simplified models in the ...
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(BMC Medica Genomics, 2020-03-06)Background Few somatic mutations have been linked to breast cancer metastasis, whereas transcriptomic differences among primary tumors correlate with incidence of metastasis, especially to the lungs and brain. However, the ...
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(BMJ Open, 2019-10)Introduction Patient-reported outcome (PRO) measures are increasingly developed with multisite, representative patient populations so that they can serve as a primary endpoint in clinical trials and longitudinal studies. ...
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(2017-01-04)Osteochondromas are common benign tumors of cartilage and bone. They are usually found as contiguous bone with a cartilage cap at the end of the growth plate of long bones. Similar to structure are extraskeletal osteochondromas. ...
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Suicide and other causes of death among Chernobyl cleanup workers from Estonia, 1986-2020: an update (European Journal Of Epidemiology, 2023-01-07)Mortality was studied in a cohort of 4831 men from Estonia who participated in the environmental cleanup of the radioac-tively contaminated areas around Chernobyl in 1986-1991. Their mortality in 1986-2020 was compared ...
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(Orthopaedic Journal of Sports Medicine, 2019-08-01)Background: Outcomes after anterior cruciate ligament reconstruction (ACLR) are not uniformly good and are worse among young female athletes. Developing better rehabilitation and return-to-sport training programs and ...
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(Journal of Patient Experience, 2019-06)Background: The significant role of lay caregivers has been explored in chronic and acute illnesses. In pregnancy, caregivers' (eg, the baby's father, friends, and family) roles in promoting the health of the mother and ...
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(Journal of Translational Medicine, 2019-12-26)Background Programmed cell death ligand-1 (PD-L1) expression on tumor cells (TCs) is associated with improved survival in patients with head and neck squamous cell carcinoma (HNSCC) treated with immunotherapy, although its ...
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(Orthopaedic Journal of Sports Medicine, 2019-08-09)Background: In the setting of anterior shoulder instability, it is important to assess the reliability of orthopaedic surgeons to diagnose pathologic characteristics on the 2 most common imaging modalities used in clinical ...
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(Scientific Reports, 2022-12-17)IOTA (International Ovarian Tumor Analysis) Simple Rules classifies adnexal masses as benign, malignant, or indeterminate based on sonographic features. We seek to determine if IOTA inappropriately directed women to surgery, ...
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(2018-09-10)Lateral condyle fractures are intra-articular injuries of the distal humerus and are the second most common elbow fracture in pediatric patients. When these fractures involve significant displacement, anatomic reduction ...
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(Clinical Lymphoma Myeloma & Leukemia, 2019-09)Approximately half of the patients with polycythemia vera experience substantial symptom burdens. We analyzed data from the ongoing Prospective Observational Study of Patients with Polycythemia Vera in US Clinical Practices ...