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Human Umbilical Tissue-Derived Cells Secrete Soluble VEGFR1 and Inhibit Choroidal Neovascularization

Cao, Jing; Yang, Rong; Smith, Taylor E.; Evans, Stephanie; McCollum, Gary W.; Pomerantz, Steven C.; Petley, Theodore; Harris, Ian R.; Penn, John S. (Molecular Therapy-Methods & Clinical Development, 2019-09-13)

Exudative age-related macular degeneration (AMD), characterized by choroidal neovascularization (CNV), is the leading cause of irreversible blindness in developed countries. Anti-vascular endothelial growth factor (VEGF) ...