Show simple item record

The Establishment of the Household Air Pollution Consortium (HAPCO)

dc.contributor.authorShu, Xiao-Ou
dc.contributor.authorYang, Gong
dc.identifier.citationHosgood, H. D., 3rd, Klugman, M., Matsuo, K., White, A. J., Sadakane, A., Shu, X. O., Lopez-Ridaura, R., Shin, A., Tsuji, I., Malekzadeh, R., Noisel, N., Bhatti, P., Yang, G., Saito, E., Rahman, S., Hu, W., Bassig, B., Downward, G., Vermeulen, R., Xue, X., … Lan, Q. (2019). The establishment of the Household Air Pollution Consortium (HAPCO). Atmosphere, 10(7), 10.3390/atmos10070422.
dc.identifier.othere-ISSN 2073-4433
dc.descriptionOnly Vanderbilt University affiliated authors are listed on VUIR. For a full list of authors, access the version of record at
dc.description.abstractHousehold air pollution (HAP) is of public health concern, with 3 billion people worldwide (including >15 million in the US) exposed. HAP from coal use is a human lung carcinogen, yet the epidemiological evidence on carcinogenicity of HAP from biomass use, primarily wood, is not conclusive. To robustly assess biomass's carcinogenic potential, prospective studies of individuals experiencing a variety of HAP exposures are needed. We have built a global consortium of 13 prospective cohorts (HAPCO: Household Air Pollution Consortium) that have site- and disease-specific mortality and solid fuel use data, for a combined sample size of 587,257 participants and 57,483 deaths. HAPCO provides a novel opportunity to assess the association of HAP with lung cancer death while controlling for important confounders such as tobacco and outdoor air pollution exposures. HAPCO is also uniquely positioned to determine the risks associated with cancers other than lung as well as nonmalignant respiratory and cardiometabolic outcomes, for which prospective epidemiologic research is limited. HAPCO will facilitate research to address public health concerns associated with HAP-attributed exposures by enabling investigators to evaluate sex-specific and smoking status-specific effects under various exposure scenarios.en_US
dc.description.sponsorshipThis works was funded in part by the Albert Einstein College of Medicine's Global Health Center, the Intramural Research Program of the NIH, National Institute of Environmental Health Sciences (Z01-ES044005) (Sisters Study), and NCI CA210286-01 (Mexican Teachers Cohort). The Radiation Effects Research Foundation (RERF), Hiroshima and Nagasaki, Japan is a public interest foundation funded by the Japanese Ministry of Health, Labor, and Welfare (MHLW) and the US Department of Energy (DOE). The BC Generations cohort was made possible through financial support from the Canadian Partnership Against Cancer and Health Canada and the BC Cancer Foundation.en_US
dc.rightsopen access publication under the terms and conditions of the Creative Commons Attribution (CC BY) license (
dc.subjectenvironmental exposuresen_US
dc.subjectcohort studiesen_US
dc.titleThe Establishment of the Household Air Pollution Consortium (HAPCO)en_US

Files in this item


This item appears in the following Collection(s)

Show simple item record